N-benzyloxycarbonyl-methionine-[2]naphthylamide, also known as Z-Met-2-Nal, is a synthetic peptide derivative that serves as a potent and selective inhibitor of the enzyme neutrophil elastase. This enzyme plays a crucial role in the degradation of extracellular matrix proteins and is implicated in various inflammatory and fibrotic diseases. The chemical structure of Z-Met-2-Nal features a benzyloxycarbonyl (Z) group, which protects the methionine residue, and a 2-naphthylamide group, which enhances the binding affinity to the enzyme's active site. N-benzyloxycarbonyl-methionine-[2]naphthylamide is often used in research to study the activity and regulation of neutrophil elastase, as well as to develop potential therapeutic agents for conditions associated with elastase dysregulation, such as emphysema, chronic obstructive pulmonary disease, and certain types of fibrosis.
3611-20-9
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Basic information
- Product Name: N-benzyloxycarbonyl-methionine-[2]naphthylamide
- Synonyms:
- CAS NO:3611-20-9
- Molecular Formula:
- Molecular Weight: 408.521
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: N-benzyloxycarbonyl-methionine-[2]naphthylamide(CAS DataBase Reference)
- NIST Chemistry Reference: N-benzyloxycarbonyl-methionine-[2]naphthylamide(3611-20-9)
- EPA Substance Registry System: N-benzyloxycarbonyl-methionine-[2]naphthylamide(3611-20-9)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 3611-20-9(Hazardous Substances Data)
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Check Digit Verification of cas no
The CAS Registry Mumber 3611-20-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,6,1 and 1 respectively; the second part has 2 digits, 2 and 0 respectively.Calculate Digit Verification of CAS Registry Number 3611-20:
(6*3)+(5*6)+(4*1)+(3*1)+(2*2)+(1*0)=59
59 % 10 = 9
So 3611-20-9 is a valid CAS Registry Number.
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N-benzyloxycarbonyl-methionine-[2]naphthylamide
