361345-40-6

Basic information

• Product Name: TERT-BUTYL 4-(3-AMINOBENZYL)PIPERAZINE-1-CARBOXYLATE
• Synonyms: 1-Piperazinecarboxylic acid, 4-[(3-aminophenyl)methyl]-, 1,1-dimethylethyl ester;4-(3-Aminobenzyl)piperazine,N1-BOCprotected97%;t-Butyl-4-(3-aminobenzyl)-1-piperazine-1-carboxylate;BUTTPARK 99\06-08;3-(1-BOC-PIPERAZIN-4-YL-METHYL)-ANILINE;4-(3-AMINOBENZYL)PIPERAZINE, N1-BOC PROTECTED;TERT-BUTYL 4-(3-AMINOBENZYL)PIPERAZINE-1-CARBOXYLATE;4-(3-Aminobenzyl)piperazine, N1-BOC protected 97%
• CAS NO: 361345-40-6
• Molecular Formula: C₁₆H₂₅N₃O₂
• Molecular Weight: 291.39
• Mol File: 361345-40-6.mol
• Article Data: 3

Chemical Properties

• Melting Point: 107 °C
• Boiling Point: 416.6 °C at 760 mmHg
• Flash Point: 205.7 °C
• Appearance: /
• Density: 1.136 g/cm³
• Vapor Pressure: 3.79E-07mmHg at 25°C
• Refractive Index: 1.567
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 6.72±0.10(Predicted)
• CAS DataBase Reference: TERT-BUTYL 4-(3-AMINOBENZYL)PIPERAZINE-1-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: TERT-BUTYL 4-(3-AMINOBENZYL)PIPERAZINE-1-CARBOXYLATE(361345-40-6)
• EPA Substance Registry System: TERT-BUTYL 4-(3-AMINOBENZYL)PIPERAZINE-1-CARBOXYLATE(361345-40-6)

Safety Data

• Hazard Codes: C
• Hazardous Substances Data: 361345-40-6(Hazardous Substances Data)

Usage

General Description

TERT-BUTYL 4-(3-AMINOBENZYL)PIPERAZINE-1-CARBOXYLATE is a chemical compound with a molecular formula C20H31N3O2. It is a piperazine derivative, specifically a tert-butyl ester of 4-(3-aminobenzyl)piperazine-1-carboxylic acid. TERT-BUTYL 4-(3-AMINOBENZYL)PIPERAZINE-1-CARBOXYLATE is commonly used as a precursor in the synthesis of pharmaceutical drugs and other organic compounds. It has potential therapeutic applications due to its ability to interact with biological receptors, making it of interest to researchers in the fields of pharmacology and medicinal chemistry. The chemical structure of TERT-BUTYL 4-(3-AMINOBENZYL)PIPERAZINE-1-CARBOXYLATE makes it an important building block for creating new drugs and chemical compounds.

InChI:InChI=1/C16H25N3O2/c1-16(2,3)21-15(20)19-9-7-18(8-10-19)12-13-5-4-6-14(17)11-13/h4-6,11H,7-10,12,17H2,1-3H3

Upstream product

• 57260-71-6 1-t-Butoxycarbonylpiperazine 
• 3958-57-4 1-bromomethyl-3-nitrobenzene 
• 203047-33-0 tert-butyl 4-(3-nitrobenzyl)piperazine-1-carboxylate 

Downstream Products

• 1117685-94-5 tert-butyl 4-[(3-{[4-(2,6-dimethylpyridin-3-yl)oxypyridin-2-yl]-amino}phenyl)-methyl]piperazine-1-carboxylate 
• 936092-44-3 4-{3-[4-(4-chloro-3-methoxy-phenylamino)-5-methyl-pyrimidin-2-ylamino]-benzyl}-piperazine-1-carboxylic acid tert butyl ester 

Relevant articles and documents

1,3,4-OXADIAZOLE SULFONAMIDE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

The present invention relates to novel compounds represented by the formula I having histone deacetylase 6 (HDAC6) inhibitory activity, stereoisomers thereof or pharmaceutically acceptable salts thereof, the use thereof for the preparation of therapeutic medicaments, pharmaceutical compositions containing the same, a method for treating diseases using the composition, and methods for preparing the novel compounds. (I) The novel compounds, stereoisomers thereof or pharmaceutically acceptable salts thereof according to the present invention have histone deacetylase (HDAC) inhibitory activity and are effective for the prevention or treatment of HDAC6-mediated diseases.

Novel lipoic acid heterocyclic or benzene derivatives, preparation and use thereof as medicines

A subject of the invention is new heterocyclic or benzenic derivatives comprising a lateral chain derived from lipoic acid, which have an inhibitory activity on NO-synthase enzymes producing nitrogen monoxide NO and/or are agents allowing the regeneration