361353-73-3

Upstream product

• 25118-23-4 ethyl 6-heptenoate 
• 105-36-2 ethyl bromoacetate 
• 64-17-5 ethanol 
• 1070-34-4 butanedioic acid, monoethyl ester 
• 1906-96-3 diethyl (4-pentenyl)malonate 
• 1119-51-3 bromopentene 
• 361353-67-5 2-ethoxycarbonyl-2-pent-4-enyl-succinic acid diethyl ester 

Relevant academic research and scientific papers

Regio- and stereoselectivity in the titanium-mediated cyclopropanation of ω-alkenoic diesters: Application in the diastereoselective synthesis of pyrrolidinone

The titanium-mediated intramolecular cyclopropanation of ω-allylic succinates leads only to cyclopropanol, arising from exclusive reactivity of one ester function. As an extension of this methodology, the diastereoselective synthesis of highly functionalized pyrrolidinone has been realized from cheap commercially available L-aspartic acid. Georg Thieme Verlag Stuttgart.

First intramolecular geminal acylation: Synthesis of bridged bicyclic diketones

Bicyclic diketones have been produced by Lewis acid-promoted geminal acylations involving cyclic acyloins tethered to an acetal. This intramolecular process must proceed via a mode of reaction which, due to steric hindrance, is not seen in the intermolecu