361382-81-2 Usage
Uses
Used in Pharmaceutical Synthesis:
1H-Imidazo[4,5-b]pyrazin-2-amine is used as a building block for the development of various pharmaceutical compounds, especially those aimed at treating central nervous system disorders. Its unique structure allows for the creation of diverse drug candidates with potential therapeutic benefits.
Used in Cancer Research:
In the field of oncology, 1H-Imidazo[4,5-b]pyrazin-2-amine is utilized as a potential anti-cancer agent. Studies have shown that it can inhibit the growth of tumor cells, making it a promising candidate for further research and development in cancer treatment.
Used in Anti-Inflammatory Applications:
1H-Imidazo[4,5-b]pyrazin-2-amine has been investigated for its anti-inflammatory properties, which could be beneficial in the treatment of various inflammatory conditions. Its potential to modulate inflammatory responses may lead to the development of new therapeutic agents for such disorders.
Used in Antiviral Research:
1H-Imidazo[4,5-b]pyrazin-2-amine has also been explored for its anti-viral properties, indicating its potential to combat viral infections. The study of 1H-Imidazo[4,5-b]pyrazin-2-amine in this context could contribute to the discovery of new antiviral drugs and treatments.
Overall, 1H-Imidazo[4,5-b]pyrazin-2-amine is a versatile and important chemical in drug discovery and development, with applications spanning multiple therapeutic areas.
Check Digit Verification of cas no
The CAS Registry Mumber 361382-81-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,6,1,3,8 and 2 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 361382-81:
(8*3)+(7*6)+(6*1)+(5*3)+(4*8)+(3*2)+(2*8)+(1*1)=142
142 % 10 = 2
So 361382-81-2 is a valid CAS Registry Number.
InChI:InChI=1/C5H5N5/c6-5-9-3-4(10-5)8-2-1-7-3/h1-2H,(H3,6,7,8,9,10)
361382-81-2Relevant articles and documents
Dienophilicity of imidazole in inverse electron demand Diels-Alder reactions: Cycloadditions with 1,2,4,5-tetrazines and the structure of zarzissine
Wan, Zhao-Kui,Woo, Grace H.C.,Snyder, John K.
, p. 5497 - 5507 (2007/10/03)
The inverse electron demand cycloadditions of 2-substituted imidazoles with dimethyl 1,2,4,5-tetrazine-3,6-dicarboxylate produced imidazo[4,5-d]pyridazines in good yields. This chemistry was applied to the synthesis of 2-amino-1H-imidazo[4,5-d]pyridazine (1), the structure reported for zarzissine, a cytotoxic marine alkaloid. Differences in the 1H- and 13C NMR spectra of 1 with those reported for zarzissine necessitated a structural revision, and zarzissine was then considered to be the corresponding 2-amino-1H-imidazo[4,5-b]pyrazine (2), which was subsequently synthesized from the parent heterocycle.
