361448-55-7Relevant articles and documents
Separation of enantiomers by lipase-catalyzed fluorous-phase delabeling
Swaleh, Sauda M,Hungerhoff, Benno,Sonnenschein, Helmut,Theil, Fritz
, p. 4085 - 4089 (2007/10/03)
Simultaneous enantiomer-selective fluorous-phase delabeling and kinetic resolution was achieved by lipase-catalyzed alcoholysis of highly fluorinated esters of racemic alcohols. The separation of the fast-reacting delabeled enantiomers and the slow-reacting fluorous-phase labeled enantiomers was performed very efficiently by partition in an organic/fluorous biphasic solvent system.