361473-14-5

Basic information

• Product Name: Benzoic acid, 3-[[(4-chlorophenyl)methylamino]sulfonyl]-
• CAS NO: 361473-14-5
• Molecular Formula: C14H12ClNO4S
• Molecular Weight: 325.773
• Mol File: 361473-14-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 3-[[(4-chlorophenyl)methylamino]sulfonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 3-[[(4-chlorophenyl)methylamino]sulfonyl]-(361473-14-5)
• EPA Substance Registry System: Benzoic acid, 3-[[(4-chlorophenyl)methylamino]sulfonyl]-(361473-14-5)

Safety Data

• Hazardous Substances Data: 361473-14-5(Hazardous Substances Data)

Upstream product

• 65-85-0 benzoic acid 
• 932-96-7 N-methyl(p-chloroaniline) 
• 4025-64-3 3-Carboxybenzenesulfonyl chloride 

Downstream Products

• 666859-61-6 3-{ [ (4-CHLOROPHENYL) (methyl) amino] sulfonyl} benzoyl chloride 
• 1586822-63-0 3-(N-(4-chlorophenyl)-N-methylsulfamoyl)-N-(4-(methylsulfinyl)phenyl)benzamide 
• 1586822-73-2 N-(4-chlorophenyl)-3-(N-(4-chlorophenyl)-N-methylsulfamoyl)-4-methoxybenzamide 
• 1586822-74-3 N-(4-chlorophenyl)-3-(N-(4-chlorophenyl)-N-methylsulfamoyl)-4-hydroxybenzamide 
• 1586822-53-8 3-(N-(4-chlorophenyl)-N-methylsulfamoyl)-N-(5-chloropyridin-2-yl)benzamide 
• 1586822-57-2 3-(N-(4-chlorophenyl)-N-methylsulfamoyl)-N-(pyridin-2-ylmethyl)benzamide 
• 1586822-84-5 3-(N-(4-chlorophenyl)-N-methylsulfamoyl)-N-(4-methylthiazol-2-yl)benzamide 
• 1586822-83-4 N-(5-bromothiazol-2-yl)-3-(N-(4-chlorophenyl)-N-methylsulfamoyl)benzamide 
• 1586822-54-9 N-(5-bromopyridin-2-yl)-3-(N-(4-chlorophenyl)-N-methylsulfamoyl)benzamide 
• 1586822-58-3 3-(N-(4-chlorophenyl)-N-methylsulfamoyl)-N-(5-fluoropyridin-2-yl)benzamide 
• 1586822-62-9 3-(N-(4-chlorophenyl)-N-methylsulfamoyl)-N-(5-hydroxypyridin-2-yl)benzamide 
• 1586822-64-1 3-(N-(4-chlorophenyl)-N-methylsulfamoyl)-N-(4-((trifluoromethyl)sulfonyl)phenyl)benzamide 
• 1586822-66-3 3-(N-(4-chlorophenyl)-N-methylsulfamoyl)-N-(pyridin-3-ylmethyl)benzamide 
• 1586822-67-4 3-(N-(4-chlorophenyl)-N-methylsulfamoyl)-N-(6-methoxypyridazin-3-yl)benzamide 

Relevant articles and documents

BENZAMIDE COMPOUNDS AND RELATED METHODS OF USE

Benzamide compounds and derivatives thereof, as can be used for selective inhibition of the SIRT2 enzyme and/or therapeutic use in the treatment of Huntington's disease.

3-(N-Arylsulfamoyl)benzamides, inhibitors of human sirtuin type 2 (SIRT2)

Inhibition of sirtuin 2 (SIRT2) is known to be protective against the toxicity of disease proteins in Parkinson's and Huntington's models of neurodegeneration. Previously, we developed SIRT2 inhibitors based on the 3-(N-arylsulfamoyl)benzamide scaffold, i