3616-58-8

Usage

Uses

Used in Chemical Synthesis:
N-(2,2-DIETHOXYETHYL)PIPERIDINE is used as a reactant for the ethylene trimerisation process, which is a chemical reaction that combines three ethylene molecules to form a propylene molecule.
Used in Pharmaceutical Industry:
N-(2,2-DIETHOXYETHYL)PIPERIDINE is used as a reactant in the synthesis of aryl-substituted piperidines. This application is crucial in the development of new pharmaceutical compounds, as aryl-substituted piperidines have potential applications in medicinal chemistry.
Used in Academic Research:
N-(2,2-DIETHOXYETHYL)PIPERIDINE is utilized in studies involving elimination reactions. These studies aim to understand the mechanisms and outcomes of elimination reactions, which are important in organic chemistry and have implications for the synthesis of various compounds.

InChI:InChI=1/C11H23NO2/c1-3-13-11(14-4-2)10-12-8-6-5-7-9-12/h11H,3-10H2,1-2H3

Upstream product

• 110-89-4 piperidine 
• 2032-35-1 Bromoacetaldehyde diethyl acetal 
• 621-62-5 chloroacetaldehyde diethyl acetal 

Downstream Products

• 54504-88-0 1-(β-ethoxy-phenethyl)-1-methyl-piperidinium; iodide 
• 36794-51-1 NSC 45070 
• 18643-56-6 2-(4-Dicyanomethyl-phenyl)-malononitrile 
• 4671-96-9 2-(piperidin-1-yl)acetaldehyde 
• 102458-15-1 3-benzyl-2-piperidinomethyl-2,3-dihydro-benzothiazole 
• 6722-47-0 1-(2-ethoxy-2-phenyl-ethyl)-piperidine 

Relevant academic research and scientific papers

Expeditious one-pot synthesis of C3-piperazinyl-substituted quinolines: Key precursors to potent c-Met inhibitors

An effective one-pot synthesis of quinolines bearing diverse C3-piperazinyl functions was developed by using a modified Friedlaender's protocol. The method not only enables the synthesis of our early reported c-Met inhibitor on a large scale, but also provides a way to generate novel multi-substituted quinolines for further structure-activity relationship (SAR) study.

Ligand effect on ethylene trimerisation with [NNN]-heteroscorpionate pyrazolyl Cr(III) catalysts

Cr(III) complexes with [NNN]-heteroscorpionate pyrazolyl ligands of the type Pz'2CHX (Pz' = pyrazol-l-yl (Pz), or 3,5-dimethylpyrazol-1-yl (PzMe); X = N-containing heterocyclic ring or amine CH 2NR1R2; R1, R2 = H or alkyl) have been prepared. Upon activation with MAO, they are active for selective ethylene trimerisation to 1-hexene. The effects of the hetero-functional group and chelate ring size on the catalytic performance have been examined. The pre-catalysts with an N-heterocycle substituent show highest activity [32400-53000 g/(g Cr h-1)] and total C6 selectivities (>97.6%) as well as 1-hexene selectivity (>96.0%) among hexenes. The X-ray single-crystal crystallographic analysis of CrCl 3[PzMe2CH2NCH2Ph] and CrCl3[PzMe2CH2NCH2Fc] (Fc = ferrocenyl) shows a tridentate coordination on the fac-octahedral Cr(III) sphere with the Cr-N bond length dependent on the N-substituent.