36166-91-3Relevant academic research and scientific papers
A flexible synthesis of privileged structural motifs using the Ollis-Sweeney ammonium ylid rearrangement
Gasiecki, Alan F.,Cross, Jeffrey L.,Henry, Rodger F.,Gracias, Vijaya,Djuric, Stevan W.
scheme or table, p. 6286 - 6288 (2009/04/06)
The Ollis-Sweeney ammonium ylid rearrangement has been effectively utilized to provide access to hitherto unknown hybrid privileged structural motifs. The rearrangement of didehydropiperidinium salts containing tethered olefins at the 4-position afforded, after subsequent ring closing metathesis, novel spirocyclic scaffolds suitable for further elaboration and incorporation of final structures into HTS sets.
