36176-31-5

Usage

Uses

Used in Pharmaceutical Industry:
2-Isopropylphenyl isothiocyanate is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its ability to react with nucleophiles makes it a valuable building block for the development of new drugs and medicinal agents.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Isopropylphenyl isothiocyanate serves as an intermediate for the production of agrochemicals. Its reactivity contributes to the creation of compounds that can be used in pest control and crop protection.
Used in Organic Synthesis:
2-Isopropylphenyl isothiocyanate is utilized as a reagent in organic synthesis, where its capacity to form a wide range of products with nucleophiles is leveraged to create diverse organic compounds for various applications.
Used in Dyes and Pigments Production:
2-ISOPROPYLPHENYL ISOTHIOCYANATE is also employed in the production of dyes and pigments, where its chemical properties contribute to the development of colorants for different industries, such as textiles, plastics, and printing inks.

InChI:InChI=1/C10H11NS/c1-8(2)9-5-3-4-6-10(9)11-7-12/h3-6,8H,1-2H3

Upstream product

• 463-71-8 thiophosgene 
• 102439-84-9 2-isopropyl-aniline; hydrochloride 
• 643-28-7 2-isopropylaniline 
• 541-41-3 chloroformic acid ethyl ester 

Downstream Products

• 25343-32-2 1-(2-isopropylphenyl)thiourea 
• 196794-89-5 3-[3-(2-isopropylphenyl)-1-ethyl-thioureido]propionic acid 
• 914638-59-8 6-chloro-2-hydroxy-3-[3-(2-isopropyl-phenyl)-thioureido]-N,N-dimethyl-benzenesulfonamide 
• 473906-06-8 C₁₃H₂₀N₂SO 
• 330479-76-0 N-(2-isopropylphenyl)-N'-(3-hydroxy-2,2-dimethyl)propylthiourea 
• 102389-19-5 2-(2-isopropylphenyl)imino-5,5-dimethyl-1,3-thiazine 

Relevant academic research and scientific papers

2-Arylimino-5,6-dihydro-4H-1,3-thiazines as a new class of cannabinoid receptor agonists. Part 1: Discovery of CB2 receptor selective compounds

2-Arylimino-5,6-dihydro-4H-1,3-thiazines have been identified as a novel class of cannabinoid agonists. A lead structure with moderate activity was discovered through a high throughput screening assay. Structure-activity relationships led to the discovery of potent agonists of CB2 receptor. The most potent compound 13 displays Ki values of >5000 and 9 nM to CB1 and CB2 receptors, respectively.

2-Arylimino-5,6-dihydro-4H-1,3-thiazines as a new class of cannabinoid receptor agonists. Part 2: Orally bioavailable compounds

Structure-activity relationships and efforts to optimize the pharmacokinetic profile of a class of 2-arylimino-5,6-dihydro-4H-1,3-thiazines as cannabinoid receptor agonists are described. Among the compounds examined, compound 14 showed potent affinity and high selectivity for CB2, and compound 23 showed potent affinities against CB1 and CB2. These compounds displayed oral bioavailability.

MEDICINAL COMPOSITION CONTAINING 1,3-THIAZINE DERIVATIVE

A compound of the formula (I) having a binding activity to the cannabinoid type 2 receptor: wherein R1 is optionally substituted heterocyclic group or the like; R2 and R2 each is independently hydrogen or the like; m is an

2-IMINO-1,3-THIAZINE DERIVATIVES

A compound of the formula (I) of the present invention selectively binds to a cannabinoid type 2 receptor (CB2R) and exhibits an antagonistic activity or agonistic activity to CB2R. wherein R1 is optionally substituted alkylene; R2 i

Synthesis of thiophene-2-carboxamidines containing 2-aminothiazoles and their biological evaluation as urokinase inhibitors

The serine protease urokinase (uPa) has been implicated in the progression of both breast and prostate cancer. Utilizing structure based design, the synthesis of a series of substituted 4-[2-amino-1,3-thiazolyl]-thiophene-2-carboxamidines is described. Further optimization of this series by substitution of the terminal amine yielded urokinase inhibitors with excellent activities.