36184-28-8Relevant academic research and scientific papers
A practical and versatile approach toward a one-pot synthesis of 2,3-disubstituted 4(3H)-quinazolinones
Dabiri, Minoo,Salehi, Peyman,Bahramnejad, Mahboobeh,Alizadeh, Mohsen
experimental part, p. 877 - 881 (2011/06/26)
An effective one-pot three-component route to 4(3H)-quinazolinones from commercially available starting materials is reported. Thus, isatoic anhydride reacted with ammonium acetate or primary amines and aldehydes in the presence of iodine to produce the corresponding quinazolinone derivatives in moderate to good yields. Springer-Verlag 2010.
An efficient synthesis of 2,3-diaryl (3H)-quinazolin-4-ones via imidoyl chlorides
Kalusa, Andrew,Chessum, Nicola,Jones, Keith
experimental part, p. 5840 - 5842 (2009/04/05)
A practical and efficient three step synthetic route to 2,3-diaryl (3H)-quinazolin-4-ones has been developed. The key step involves microwave-assisted condensation of an imidoyl chloride with an aryl amine. This methodology affords the products cleanly and in high yields.
