36201-04-4Relevant academic research and scientific papers
A simple Lewis acid induced reaction of phenols with electrophiles: Synthesis of functionalized 4H-chromenes and ortho-benzylphenols
Sreenivasulu, Chinnabattigalla,Thadathil, Ditto Abraham,Pal, Sumit,Gedu, Satyanarayana
, p. 112 - 122 (2019/11/19)
Lewis acid ZnCl2 promoted cyclization protocol to 4H-chromenes is accomplished, using readily available phenols and acetophenones as starting materials. Interestingly, the process is feasible under the solvent free environment. Synthesis of a variety of 4H-chromenes have been accomplished using this strategy. In addition, this concept is extended to the synthesis of ortho-benzylphenols by treating phenols either with styrenes or secondary benzylic alcohols.
Zirconocene bis(perfluorooctanesulfonate) s-catalyzed highly efficient synthesis of 1,3,5-triaryl benzene via cyclotrimerization of ketones
Zhang, Guo Ping,Qiu, Ren Hua,Xu, Xin Hua,Zhou, Hai Hui,Kuang, Ya Fei,Chen, Si Hai
experimental part, p. 858 - 864 (2012/01/19)
Air-stable zirconocene bis(perfluoroctanesulfonate) s [Cp 2Zr]OSO2C8F17) 2] (1) with high Lewis acidity and high thermal stability was prepared by the reaction between Cp2ZrCl2 a
A selective solvent-free self-condensation of carbonyl compounds utilizing microwave irradiation
Sharma, Lalit Kumar,Kim, Kyung Bo,Elliott, Gregory I.
supporting information; experimental part, p. 1546 - 1549 (2011/07/31)
An environmentally benign microwave-assisted solvent-free self-condensation of carbonyl compounds was developed using catalytic amounts of triethylamine and lithium perchlorate. Changing the amount of lithium perchlorate helps in controlling the ratio of the single-condensation and double-condensation products. The effect of other additives and microwave activation was also investigated. The optimized conditions were then applied to various cyclic/acyclic ketones and aldehydes, with selectivity observed in many cases.
Increased conversion to 2,4,6-triarylpyrylium salt: Aldol cyclotrimerization of acetophenone in BMImPF6 ionic liquid
Chuang, Po-Neng,Wu, Tsao-Dong,Liu, Ling-Kang
experimental part, p. 512 - 516 (2009/05/11)
Substituted acetophenone 1 in BMImPF6 ionic liquid, heated at 120 °C for 24 h, produces β-methylchalcone 2, triarylbenzene 3, and triarylpyrylium salt 4. BMImPF6 catalyzes the self-aldol condensation of 1, whose cyclotrimerization gi
Alkylation of α-Halo Diketones via Enol Phosphate Intermediate
Onishi, Jim Yoshitaka,Takuwa, Tomofumi,Mukaiyama, Teruaki
, p. 994 - 995 (2007/10/03)
β-Substituted α,β-unsaturated carbonyl compounds were obtained in moderate to high yields by a 1,4-addition of organocuprates to enol phosphate intermediates formed in situ from triethyl phosphite and 2-bromo-1,3-dicarbonyl compounds.
2-(1,3-Diazacycloalkenyl)-2-hydrazones of substituted chalcones
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, (2008/06/13)
The preparation of 2-(1,3-Diazacycloalkenyl)-2-hydrazones of substituted chalcones is described. These compounds are useful as anti-tubercular agents in warm-blooded animals.
