36207-43-9 Usage
Description
AMINO ACID HYDROXAMATES DL-METHIONINE HYDROXAMATE is a derivative of the essential amino acid methionine, featuring a hydroxamate group that acts as a potent chelator of metal ions. AMINO ACID HYDROXAMATES DL-METHIONINE HYDROXAMATE is known for its potential applications in pharmaceuticals, medical research, and biotechnology due to its ability to inhibit various enzymes. However, its toxicity and adverse effects require extensive study.
Uses
Used in Pharmaceutical Industry:
AMINO ACID HYDROXAMATES DL-METHIONINE HYDROXAMATE is used as an enzyme inhibitor for its ability to chelate metal ions, which are often essential for the activity of certain enzymes. This property makes it a potential candidate for the development of drugs targeting specific enzymes involved in diseases.
Used in Medical Research:
In the field of medical research, AMINO ACID HYDROXAMATES DL-METHIONINE HYDROXAMATE serves as a valuable tool for studying enzyme mechanisms and their roles in various biological processes. Its metal-chelating properties allow researchers to investigate the effects of metal ion modulation on enzyme function and regulation.
Used in Biotechnology:
AMINO ACID HYDROXAMATES DL-METHIONINE HYDROXAMATE is utilized in biotechnology for its potential applications in the development of novel therapeutic agents and diagnostic tools. Its ability to interact with metal ions and inhibit enzymes can be harnessed to create targeted therapies and biosensors for various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 36207-43-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,6,2,0 and 7 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 36207-43:
(7*3)+(6*6)+(5*2)+(4*0)+(3*7)+(2*4)+(1*3)=99
99 % 10 = 9
So 36207-43-9 is a valid CAS Registry Number.
36207-43-9Relevant articles and documents
Methionine analogues as inhibitors of methionyl-tRNA synthetase
Lee, Jeewoo,Kang, Mee Kyoung,Chun, Moon Woo,Jo, Yeong Joon,Kwak, Jin Hwan,Kim, Sunghoon
, p. 3511 - 3514 (2007/10/03)
A series of methionine analogues have been synthesized as inhibitors of methionyl-tRNA synthetase and evaluated for their inhibitory activities of E. coli methionyl-tRNA synthetase and bacterial growth. Among them, L-methionine hydroxamate 20 has proved to be the best inhibitor of the enzyme with K(i) = 19 μM and showed a growth inhibition against E. coli JM 109, P. vulganis 6059 and C. freundii 8090.