36207-43-9

Basic information

• Product Name: AMINO ACID HYDROXAMATES DL-METHIONINE HYDROXAMATE
• Synonyms: AMINO ACID HYDROXAMATES DL-METHIONINE HYDROXAMATE;DL-METHIONINE HYDROXAMATE
• CAS NO: 36207-43-9
• Molecular Formula: C₅H₁₂N₂O₂S
• Molecular Weight: 164.23
• Product Categories: Amino Acids;I - Z;Modified Amino Acids
• Mol File: 36207-43-9.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Storage Temp.: −20°C
• CAS DataBase Reference: AMINO ACID HYDROXAMATES DL-METHIONINE HYDROXAMATE(CAS DataBase Reference)
• NIST Chemistry Reference: AMINO ACID HYDROXAMATES DL-METHIONINE HYDROXAMATE(36207-43-9)
• EPA Substance Registry System: AMINO ACID HYDROXAMATES DL-METHIONINE HYDROXAMATE(36207-43-9)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 36207-43-9(Hazardous Substances Data)

Usage

Description

AMINO ACID HYDROXAMATES DL-METHIONINE HYDROXAMATE is a derivative of the essential amino acid methionine, featuring a hydroxamate group that acts as a potent chelator of metal ions. AMINO ACID HYDROXAMATES DL-METHIONINE HYDROXAMATE is known for its potential applications in pharmaceuticals, medical research, and biotechnology due to its ability to inhibit various enzymes. However, its toxicity and adverse effects require extensive study.

Uses

Used in Pharmaceutical Industry:
AMINO ACID HYDROXAMATES DL-METHIONINE HYDROXAMATE is used as an enzyme inhibitor for its ability to chelate metal ions, which are often essential for the activity of certain enzymes. This property makes it a potential candidate for the development of drugs targeting specific enzymes involved in diseases.
Used in Medical Research:
In the field of medical research, AMINO ACID HYDROXAMATES DL-METHIONINE HYDROXAMATE serves as a valuable tool for studying enzyme mechanisms and their roles in various biological processes. Its metal-chelating properties allow researchers to investigate the effects of metal ion modulation on enzyme function and regulation.
Used in Biotechnology:
AMINO ACID HYDROXAMATES DL-METHIONINE HYDROXAMATE is utilized in biotechnology for its potential applications in the development of novel therapeutic agents and diagnostic tools. Its ability to interact with metal ions and inhibit enzymes can be harnessed to create targeted therapies and biosensors for various diseases and conditions.

Upstream product

• 59-51-8 DL-methionine 
• 93000-03-4 N-(t-butoxycarbonyl)methionine 
• 452-95-9 methionine ethyl ester 

Downstream Products

• 119197-49-8 1-hydroxy-6-methyl-2-oxo-5-phenyl-3-(3-thiabutyl)-1,2-dihydropyrazine 
• 119197-48-7 5,6-diphenyl-1-hydroxy-2-oxo-3-(3-thiabutyl)-1,2-dihydropyrazine 
• 119197-47-6 5,6-dimethyl-1-hydroxy-2-oxo-3-(3-thiabutyl)-1,2-dihydropyrazine 

Relevant articles and documents

Methionine analogues as inhibitors of methionyl-tRNA synthetase

A series of methionine analogues have been synthesized as inhibitors of methionyl-tRNA synthetase and evaluated for their inhibitory activities of E. coli methionyl-tRNA synthetase and bacterial growth. Among them, L-methionine hydroxamate 20 has proved to be the best inhibitor of the enzyme with K(i) = 19 μM and showed a growth inhibition against E. coli JM 109, P. vulganis 6059 and C. freundii 8090.