36215-16-4

Basic information

• Product Name: (E)-methyl 5,5-dimethylhex-2-enoate
• CAS NO: 36215-16-4
• Molecular Weight: 156.225
• Mol File: 36215-16-4.mol

Chemical Properties

• CAS DataBase Reference: (E)-methyl 5,5-dimethylhex-2-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-methyl 5,5-dimethylhex-2-enoate(36215-16-4)
• EPA Substance Registry System: (E)-methyl 5,5-dimethylhex-2-enoate(36215-16-4)

Safety Data

• Hazardous Substances Data: 36215-16-4(Hazardous Substances Data)

Upstream product

• 15672-88-5 neohexyliodide 
• 624-95-3 3,3-dimethylbutanol 

Relevant articles and documents

Electrophilic Iron Catalyst Paired with a Lithium Cation Enables Selective Functionalization of Non-Activated Aliphatic C?H Bonds via Metallocarbene Intermediates

Combining an electrophilic iron complex [Fe(Fpda)(THF)]2 (3) [Fpda=N,N′-bis(pentafluorophenyl)-o-phenylenediamide] with the pre-activation of α-alkyl-substituted α-diazoesters reagents by LiAl(ORF)4 [ORF=(OC(CF3)3] provides unprecedented access to selective iron-catalyzed intramolecular functionalization of strong alkyl C(sp3)?H bonds. Reactions occur at 25 °C via α-alkyl-metallocarbene intermediates, and with activity/selectivity levels similar to those of rhodium carboxylate catalysts. Mechanistic investigations reveal a crucial role of the lithium cation in the rate-determining formation of the electrophilic iron-carbene intermediate, which then proceeds by concerted insertion into the C?H bond.