3622-32-0

Basic information

• Product Name: 2-Chloro-4-methylbenzothiazole
• Synonyms: IFLAB-BB F1910-0001;2-CHLORO-4-METHYL-BENZOTHIOZOLE;2-CHLORO-4-METHYL-1,3-BENZOTHIAZOLE;2-CHLORO-4-METHYLBENZOTHIAZOLE;Benzothiazole, 2-chloro-4-methyl- (6CI,7CI,8CI,9CI);2-chloro-4-methylbenzo[d]thiazole
• CAS NO: 3622-32-0
• Molecular Formula: C₈H₆ClNS
• Molecular Weight: 183.66
• Product Categories: BENZOTHIAZOLE
• Mol File: 3622-32-0.mol
• Article Data: 5

Chemical Properties

• Melting Point: 49-50 °C
• Boiling Point: 268.4°Cat760mmHg
• Flash Point: 116.1°C
• Appearance: /
• Density: 1.365g/cm³
• Vapor Pressure: 0.0127mmHg at 25°C
• Refractive Index: 1.67
• Storage Temp.: 2-8°C
• PKA: 0.32±0.10(Predicted)
• CAS DataBase Reference: 2-Chloro-4-methylbenzothiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-4-methylbenzothiazole(3622-32-0)
• EPA Substance Registry System: 2-Chloro-4-methylbenzothiazole(3622-32-0)

Safety Data

• Hazardous Substances Data: 3622-32-0(Hazardous Substances Data)

Usage

Chemical Properties

White solid

Uses

2-Chloro-4-methyl-benzothiazole, is an intermediate in the preparation of heteroaryl sulfonamides and aminotriazole.

InChI:InChI=1/C8H6ClNS/c1-5-3-2-4-6-7(5)10-8(9)11-6/h2-4H,1H3

Upstream product

• 1477-42-5 4-methyl-1,3-benzothiazol-2-amine 
• 20174-68-9 4-methyl-2-hydrazinobenzothiazole 

Downstream Products

• 20174-68-9 4-methyl-2-hydrazinobenzothiazole 
• 1095340-76-3 N-(4-(4-methylbenzo[d]thiazol-2-yl)phenyl)-1-(thiophen-2-ylsulfonyl)piperidine-4-carboxamide 
• 1340598-21-1 N-{2-[4-(aminosulfonyl)phenyl]ethyl}-1-(4-methyl-1,3-benzothiazol-2-yl)-3-piperidinecarboxamide 
• 3622-20-6 4-methyl-2-methylsulfanyl-1,3-benzothiazole 

Relevant articles and documents

DERIVATIVES OF HETEROARYLSULFONAMIDES, THEIR PREPARATION AND THEIR APPLICATION IN HUMAN THERAPY

The present invention concerns derivatives of heteroarylsulfonamides, notably as blockers of Kv potassium channels, and more particularly of channels Kv1.5, Kv4.3 or Kv11.1, their application in clinical therapy and their preparation methods. These compounds correspond to the following general formula (I): where R1 represents one or more substituents of the phenyl core X such as: hydrogen, halogen, trifluoromethyl, trifluoromethoxy, linear or branched C1-C4 alkyl, or linear or branched C1-C4 alkoxy, A represents oxygen or sulphur, B represents nitrogen when n=1 or 2 and D represents —C(═O)—, or B represents CH when n=0 and D represents —CH2O— or when n=1 and D represents —O—, R2 represents a hydrogen, a methyl, a fluorine or chlorine atom or a methoxy, HetAr represents a pyridyl or quinolyl group, possibly substituted by a group such as a linear or branched C1-C4 alkyl, a linear or branched C1-C4 alkoxy, a halogen, or a trifluoromethyl, and to their pharmaceutically acceptable salts.

Preparation and use of aryl alkyl acid derivatives for the treatment of obesity

This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.

Basic ethers of 2-anilinobenzothiazoles and 2-anilinobenzoxazoles as potential antidepressants.

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