3622-35-3

Basic information

• Product Name: BENZOTHIAZOLE-6-CARBOXYLIC ACID
• Synonyms: BUTTPARK 29\06-35;BENZOTHIAZOLE-6-CARBOXYLIC ACID;6-BENZOTHIAZOLECARBOXYLIC ACID;1,3-BENZOTHIAZOLE-6-CARBOXYLIC ACID;1,3-Benzothiazole-6-carboxylic acid, tech;6-Benzothiazolecarboxylicacid(6CI,7CI,8CI,9CI);benzo[d]thiazole-6-carboxylic acid;1,3-Benzothiazole-6-carboxylic acid ,98%
• CAS NO: 3622-35-3
• Molecular Formula: C₈H₅NO₂S
• Molecular Weight: 179.2
• Product Categories: BENZOTHIAZOLE;Carboxylic Acids;Thiazoles, Isothiazoles &Benzothiazoles;Carboxylic Acids;Thiazoles, Isothiazoles & Benzothiazoles;Building Blocks;Heterocyclic Building Blocks;Thiazoles
• Mol File: 3622-35-3.mol
• Article Data: 3

Chemical Properties

• Melting Point: 245-251 °C(lit.)
• Boiling Point: 387.668 °C at 760 mmHg
• Flash Point: 188.255 °C
• Appearance: White to pale brown/Powder
• Density: 1.508 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.732
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 3.70±0.30(Predicted)
• CAS DataBase Reference: BENZOTHIAZOLE-6-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: BENZOTHIAZOLE-6-CARBOXYLIC ACID(3622-35-3)
• EPA Substance Registry System: BENZOTHIAZOLE-6-CARBOXYLIC ACID(3622-35-3)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-20/21/22
• Safety Statements: 26-36-26 37/39
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 3622-35-3(Hazardous Substances Data)

Usage

Chemical Properties

white to light yellow crystal powde

Uses

Benzothiazole-6-carboxylic acid may be used in the synthesis of N-(pyridin-4-yl)benzo[d]thiazole-6-carboxamide, which shows the potential to inhibit K1 capsule formation in uropathogenic Escherichia coli. It may also be used as an internal standard during the quantification of benzothiazoles by liquid chromatography-electrospray ionization-tandem mass spectrometry.

General Description

Benzothiazole-6-carboxylic acid (BTCA) is a benzothiazole derivative.

InChI:InChI=1/C8H5NO2S/c10-8(11)5-1-2-6-7(3-5)12-4-9-6/h1-4H,(H,10,11)

Upstream product

• 2942-15-6 6-methylbenzothiazole 
• 58249-61-9 6-cyano benzothiazole 
• 23451-96-9 2-amino-5-methylthiophenol 
• 114224-05-4 ethyl 4-amino-3-thiocyanatobenzoate 

Downstream Products

• 73931-63-2 methyl 1,3-benzothiazole-6-carboxylate 
• 95-16-9 1,3-Benzothiazole 
• 95-15-8 Benzo[b]thiophene 
• 55439-73-1 1,3-benzothiazole-6-carboxylic acid chloride 
• 6941-28-2 2-methyl-1,3-benzothiazole-6-carboxylic acid 
• 1029431-44-4 C₁₅H₁₆N₂OS 
• 1029431-13-7 C₃₃H₃₆N₆O₆S 
• 1005205-14-0 tert-butyl 2-(1,3-benzothiazol-6-ylcarbonyl)hydrazinecarboxylate 
• 1148155-51-4 benzothiazole-6-carboxylic acid (4-hydroxy-butyl)-amide 
• 300852-46-4 4-amino-3-sulfobenzoic acid 
• 1392323-50-0 C₁₇H₁₃BrN₂OS 
• 1392323-22-6 C₁₇H₁₄N₂OS 
• 1202182-83-9 N-(3-(2-methoxyethoxy)phenyl)methyl-benzothiazole-6-carboxamide 
• 1202182-73-7 N-(3-(3-methoxypropoxy)phenyl)methyl-benzothiazole-6-carboxamide 

Relevant articles and documents

FIBROSIS INHIBITOR

Medicament being useful as a fibrosis inhibitor for organs or tissues, which comprises a compound of the formula (I): wherein Ring Z is optionally substituted pyrrole ring, etc.; W2 is -CO-, -SO2-, optionally substituted C1-C4 alkylene, etc.; Ar2 is optionally substituted aryl, etc.; W1 and Ar1 mean the following (1) and (2):(1) W1 is optionally substituted C1-C4 alkylene, etc.; Ar1 is optionally substituted bicyclic heteroaryl having 1 to 4 nitrogen atoms as ring-forming atoms:(2) W1 is optionally substituted C2-C5 alkylene, optionally substituted C2-C5 alkenylene, etc.; and Ar1 is aryl or monocyclic heteroaryl, which is substituted by carboxyl, alkoxycarbonyl, etc. at the ortho- or meta-position thereof with respect to the binding position of W1, or a pharmaceutically acceptable salt thereof.

PEPTIDYL HETEROCYCLES USEFUL IN THE TREATMENT OF THROMBIN RELATED DISORDERS

Compounds of the Formula I: STR1 useful in the treatment of thrombin and trypsin related disorders.