3622-39-7

Basic information

• Product Name: 2-BROMO-4-METHOXYBENZOTHIAZOLE
• Synonyms: 2-BROMO-4-METHOXYBENZOTHIAZOLE;2-Bromo-4-methoxybenzo[d]thiazole
• CAS NO: 3622-39-7
• Molecular Formula: C₈H₆BrNOS
• Molecular Weight: 244.11
• Mol File: 3622-39-7.mol
• Article Data: 3

Chemical Properties

• Melting Point: 71 °C
• Boiling Point: 335.4±34.0 °C(Predicted)
• Appearance: /
• Density: 1.666±0.06 g/cm3(Predicted)
• PKA: -0.08±0.10(Predicted)
• CAS DataBase Reference: 2-BROMO-4-METHOXYBENZOTHIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-4-METHOXYBENZOTHIAZOLE(3622-39-7)
• EPA Substance Registry System: 2-BROMO-4-METHOXYBENZOTHIAZOLE(3622-39-7)

Safety Data

• Hazardous Substances Data: 3622-39-7(Hazardous Substances Data)

Usage

General Description

2-Bromo-4-methoxybenzothiazole, also known as Bromomethoxybenzothiazole, is a specialty chemical that typically appears as a light yellow powder. 2-BROMO-4-METHOXYBENZOTHIAZOLE belongs to the family of Benzothiazoles, which are aromatic compounds containing a benzene fused to a thiazole ring. Although further research is required to fully understand its potential applications, benzothiazoles are generally used in research, pharmaceuticals, and chemical industries due to their vast array of biological activities. As with many chemicals, it's important to handle 2-Bromo-4-methoxybenzothiazole with care due to its potential hazards.

Upstream product

• 5464-79-9 4-methoxy-1,3-benzothiazol-2-amine 

Downstream Products

• 940287-39-8 2-(4-fluorophenyl)-4-methoxybenzo[d]thiazole 
• 7267-30-3 4-methoxybenzo[d]thiazole-2-carbonitrile 

Relevant articles and documents

BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS

Disclosed are compounds of Formula (I) to (VIII): (I) (II) (III) (IV) (V) (VI) (VII) (VIII); or a stereoisomer, tautomer, pharmaceutically acceptable salt, solvate or prodrug thereof, wherein R3 is a bicyclic heteroaryl group substituted with zero to 3 R3a; and R1, R2, R3a, R4, and n are defined herein. Also disclosed are methods of using such compounds as PAR4 inhibitors, and pharmaceutical compositions comprising such compounds. These compounds are useful in inhibiting or preventing platelet aggregation, and are useful for the treatment of a thromboembolic disorder or the primary prophylaxis of a thromboembolic disorder.

Thiazolobenzyne: A versatile intermediate for multisubstituted benzothiazoles

Thiazolobenzyne, which is a benzyne species fused with a thiazole ring, was efficiently generated via an iodine-magnesium exchange reaction of an ortho-iodoaryl triflate-type precursor using a trimethylsilylmethyl Grignard reagent as an activator. A wide range of arynophiles reacted efficiently with the thiazolobenzynes generated by this method to afford various multisubstituted benzothiazoles.