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N4-benzoyl-1-(2',3',4',6'-tetra-O-acetyl-β-D-glucopyranosyl)-cytosine is a complex organic compound that combines a cytosine base with a benzoyl group and a tetra-O-acetyl-β-D-glucopyranosyl moiety. N4-benzoyl-1-(2’,3’,4’,6’-tetra-O-acetyl-β-D-glucopyranosly)-cytosine is characterized by the presence of a cytosine molecule, which is a pyrimidine base found in DNA and RNA, linked to a benzoyl group that provides additional stability and reactivity. The tetra-O-acetyl-β-D-glucopyranosyl group is a modified sugar molecule, where four hydroxyl groups are acetylated, which can protect the sugar from unwanted reactions and can be used as a protecting group in organic synthesis. This chemical structure is of interest in the field of medicinal chemistry, particularly in the development of antiviral drugs, as it can mimic the structure of nucleosides and potentially interfere with viral replication processes. The compound's specific arrangement and protective groups make it a candidate for further study in the context of drug design and synthesis.

3624-41-7

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3624-41-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 3624-41-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,6,2 and 4 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 3624-41:
(6*3)+(5*6)+(4*2)+(3*4)+(2*4)+(1*1)=77
77 % 10 = 7
So 3624-41-7 is a valid CAS Registry Number.

3624-41-7Downstream Products

3624-41-7Relevant academic research and scientific papers

A general method for N-glycosylation of nucleobases promoted by (p-Tol)2SO/Tf2O with thioglycoside as donor

Liu, Guang-Jian,Zhang, Xiao-Tai,Xing, Guo-Wen

supporting information, p. 12803 - 12806 (2015/08/06)

Based on a preactivation strategy using the (p-Tol)2SO/Tf2O system, a series of nucleosides were synthesized by coupling various thioglycosides with pyrimidines and purines under mild conditions. High yields and excellent β-stereoselectivities were obtained with either armed or disarmed N-glycosylation donors by tuning the amount of (p-Tol)2SO additive.

An efficient approach to the synthesis of nucleosides: Gold(I)-catalyzed N-glycosylation of pyrimidines and purines with glycosyl ortho-alkynyl benzoates

Zhang, Qingju,Sun, Jiansong,Zhu, Yugen,Zhang, Fuyi,Yu, Biao

supporting information; experimental part, p. 4933 - 4936 (2011/06/24)

Persuaded with gold: The title reaction in the presence of [Ph 3PAuNTf2] (Tf=trifluoromethanesulfonyl) led conveniently to the corresponding nucleosides with excellent regioselectivity (see scheme). Even purine derivatives underwent this transformation owing to the mild conditions, which enabled the use of protecting groups that would not usually be compatible with N-glycosylation conditions. Copyright

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