28244-94-2 Usage
Description
4-Methylphenyl 2,3,4,6-tetra-O-acetyl-1-thio-b-D-glucopyranoside is a thio-glycoside derivative of glucose with the molecular formula C21H26O11S. It is characterized by the presence of a methylphenyl group and four acetyl groups, which contribute to its stability and reactivity. This chemical compound is widely used in organic synthesis and chemical research as a building block and intermediate for the preparation of other complex organic compounds.
Uses
Used in Organic Synthesis:
4-Methylphenyl 2,3,4,6-tetra-O-acetyl-1-thio-b-D-glucopyranoside is used as a building block in organic synthesis for the preparation of various complex organic compounds. Its unique structure and reactivity make it a valuable component in the synthesis of a wide range of molecules.
Used in Chemical Research:
In the field of chemical research, 4-Methylphenyl 2,3,4,6-tetra-O-acetyl-1-thio-b-D-glucopyranoside serves as an intermediate for the development of new chemical reactions and methodologies. Its diverse applications in chemistry and biochemistry make it an essential tool for researchers exploring novel synthetic pathways and mechanisms.
Used in Pharmaceutical Industry:
4-Methylphenyl 2,3,4,6-tetra-O-acetyl-1-thio-b-D-glucopyranoside is used as a key intermediate in the synthesis of pharmaceutical compounds. Its unique chemical properties and reactivity enable the development of new drugs with potential therapeutic applications.
Used in Biochemical Research:
In biochemical research, 4-Methylphenyl 2,3,4,6-tetra-O-acetyl-1-thio-b-D-glucopyranoside is employed as a starting material for the preparation of bioactive molecules and glycoconjugates. Its ability to form stable glycosidic linkages makes it a valuable tool for studying carbohydrate-based interactions and their biological implications.
Overall, 4-Methylphenyl 2,3,4,6-tetra-O-acetyl-1-thio-b-D-glucopyranoside is a versatile chemical compound with diverse applications in various industries, including organic synthesis, chemical research, pharmaceuticals, and biochemistry. Its unique structure and reactivity make it an essential component in the development of new compounds and methodologies.
Check Digit Verification of cas no
The CAS Registry Mumber 28244-94-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,2,4 and 4 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 28244-94:
(7*2)+(6*8)+(5*2)+(4*4)+(3*4)+(2*9)+(1*4)=122
122 % 10 = 2
So 28244-94-2 is a valid CAS Registry Number.
28244-94-2Relevant articles and documents
Synthesis method of voglibose
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Paragraph 0060- 0061; 0065-0067, (2021/08/07)
The invention provides a synthesis method of voglibose, and solves the technical problems that in an existing synthesis method of voglibose, raw materials are difficult to obtain, high in price, large in investment, low in yield and not suitable for industrial production. The synthesis method comprises the steps: synthesizing a compound V by taking glucose monohydrate and sodium acetate as raw materials through eleven reaction steps; and preparing a compound VIII from the compound V through an addition reaction, a ring-opening reaction and an aldol condensation reaction, and thus obtaining voglibose through amination reduction of the compound VIII. The synthesis method of voglibose can be widely applied to the technical field of voglibose synthesis methods.
Transition-metal-free synthesis of aryl 1-thioglycosides with arynes at room temperature
Liao, Li-Hua,Liu, Yao,Yan, Nan,Yu, Xiao-Bing,Zhang, Xiang-Mei,Zhong, Qian
, p. 26666 - 26671 (2021/08/17)
A mild, convenient and transition-metal-free protocol for the synthesis of aryl 1-thioglycosides is presentedviaarynes generatedin situcombined with glycosyl thiols in the presence of TBAF(tBuOH)4. The methodology provides a general and efficient way to prepare a series of functionalized thioglycosides in good to excellent yields with a perfect control of the anomeric configuration at room temperature. In addition, the reaction conditions tolerate a variety of the pentoses and hexoses, and the reaction also performs smoothly on protected monosaccharides and disaccharides.
A Synthetic Carbohydrate-Protein Conjugate Vaccine Candidate against Klebsiella pneumoniae Serotype K2
Ravinder, Mettu,Liao, Kuo-Shiang,Cheng, Yang-Yu,Pawar, Sujeet,Lin, Tzu-Lung,Wang, Jin-Town,Wu, Chung-Yi
, p. 15964 - 15997 (2020/11/13)
Klebsiella pneumoniae causes pneumonia and liver abscesses in humans worldwide and contains virulence factor capsular polysaccharides and lipopolysaccharides linked to the cell wall. Although capsular polysaccharides are good antigens for vaccine producti