28244-94-2 Usage
Description
4-Methylphenyl 2,3,4,6-tetra-O-acetyl-1-thio-b-D-glucopyranoside is a thio-glycoside derivative of glucose with the molecular formula C21H26O11S. It is characterized by the presence of a methylphenyl group and four acetyl groups, which contribute to its stability and reactivity. This chemical compound is widely used in organic synthesis and chemical research as a building block and intermediate for the preparation of other complex organic compounds.
Uses
Used in Organic Synthesis:
4-Methylphenyl 2,3,4,6-tetra-O-acetyl-1-thio-b-D-glucopyranoside is used as a building block in organic synthesis for the preparation of various complex organic compounds. Its unique structure and reactivity make it a valuable component in the synthesis of a wide range of molecules.
Used in Chemical Research:
In the field of chemical research, 4-Methylphenyl 2,3,4,6-tetra-O-acetyl-1-thio-b-D-glucopyranoside serves as an intermediate for the development of new chemical reactions and methodologies. Its diverse applications in chemistry and biochemistry make it an essential tool for researchers exploring novel synthetic pathways and mechanisms.
Used in Pharmaceutical Industry:
4-Methylphenyl 2,3,4,6-tetra-O-acetyl-1-thio-b-D-glucopyranoside is used as a key intermediate in the synthesis of pharmaceutical compounds. Its unique chemical properties and reactivity enable the development of new drugs with potential therapeutic applications.
Used in Biochemical Research:
In biochemical research, 4-Methylphenyl 2,3,4,6-tetra-O-acetyl-1-thio-b-D-glucopyranoside is employed as a starting material for the preparation of bioactive molecules and glycoconjugates. Its ability to form stable glycosidic linkages makes it a valuable tool for studying carbohydrate-based interactions and their biological implications.
Overall, 4-Methylphenyl 2,3,4,6-tetra-O-acetyl-1-thio-b-D-glucopyranoside is a versatile chemical compound with diverse applications in various industries, including organic synthesis, chemical research, pharmaceuticals, and biochemistry. Its unique structure and reactivity make it an essential component in the development of new compounds and methodologies.
Check Digit Verification of cas no
The CAS Registry Mumber 28244-94-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,2,4 and 4 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 28244-94:
(7*2)+(6*8)+(5*2)+(4*4)+(3*4)+(2*9)+(1*4)=122
122 % 10 = 2
So 28244-94-2 is a valid CAS Registry Number.
28244-94-2Relevant articles and documents
Concise Synthesis of 1-Thioalkyl Glycoside Donors by Reaction of Per-O-acetylated Sugars with Sodium Alkanethiolates under Solvent-Free Conditions
Dong, Hai,Feng, Guang-Jing,Guo, Yang-Fan,Liu, Chun-Yang,Luo, Tao
, (2022/02/07)
A relatively green method for synthesizing 1-thioalkyl glycosides has been developed, where sodium alkanethiolates were used to react with per-O-acetylated sugars instead of odorous alkyl mercaptans in the presence of BF3·Et2O without the use of solvents under mild conditions. Furthermore, we found that 1,2-trans-β-thioglycosides can be converted into corresponding 1,2-cis-α-thioglycosides in the presence of trifluoromethanesulfonic acid in nonpolar solvents under mild conditions. This provides a simple and efficient new approach for synthesizing challenging 1,2-cis-α-thioglycosides.
Site-Selective Acylation of Pyranosides with Oligopeptide Catalysts
Seitz, Alexander,Wende, Raffael C.,Roesner, Emily,Niedek, Dominik,Topp, Christopher,Colgan, Avene C.,McGarrigle, Eoghan M.,Schreiner, Peter R.
, p. 3907 - 3922 (2021/03/09)
Herein, we report the oligopeptide-catalyzed site-selective acylation of partially protected monosaccharides. We identified catalysts that invert site-selectivity compared to N-methylimidazole, which was used to determine the intrinsic reactivity, for 4,6
Synthesis of type 1 Lewis b hexasaccharide antigen structures featuring flexible incorporation of l-[U-13C6]-fucose for NMR binding studies
Lahmann, Martina,Long, Mark,Ní Cheallaigh, Aisling,Oscarson, Stefan,Reihill, Mark
, p. 4452 - 4458 (2020/10/20)
While 13C-labelled proteins are common tools in NMR studies, lack of access to 13C-labelled carbohydrate structures has restricted their use. l-Fucose is involved in a wide range of physiological and pathophysiological processes in mammalian organisms. He
