362488-31-1Relevant articles and documents
Cyclic beta-amino acid derivatives as inhibitors of matrix metalloproteases and TNF-alpha
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, (2008/06/13)
The present application describes novel cyclic β-amino acid derivatives of formula I: or pharmaceutically acceptable salt forms thereof, wherein ring B is a 5-7 membered cyclic system containing from 0-2 heteroatoms selected from O, N, NRa, and S(O)p, and 0-1 carbonyl groups and the other variables are defined in the present specification, which are useful as metalloprotease and/or as TNF-α inhibitors.