56826-61-0

Basic information

• Product Name: (2-METHYL-PYRIDIN-3-YL)-METHANOL
• Synonyms: 3-METHYL-3-HYDROXYMETHYL PYRIDINE;3-(HYDROXYMETHYL)-ALPHA-PICOLINE;3-Hydroxymethyl-2-methylpyridine;3-Pyridinemethanol, 2-methyl-;(2-Mehtyl-pyridin-3-yl)-methanol;2-Methyl-3-PyridineMethanol;(2-Methylpyridine-3-yl)Methanol;2-Methyl-3-hydroxyMethyl pyridine 97%
• CAS NO: 56826-61-0
• Molecular Formula: C₇H₉NO
• Molecular Weight: 123.15
• EINECS: -0
• Mol File: 56826-61-0.mol
• Article Data: 21

Chemical Properties

• Boiling Point: 262 °C(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.106 g/mL at 25 °C(lit.)
• Vapor Pressure: 2.234mmHg at 25°C
• Refractive Index: n20/D 1.545(lit.)
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: (2-METHYL-PYRIDIN-3-YL)-METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (2-METHYL-PYRIDIN-3-YL)-METHANOL(56826-61-0)
• EPA Substance Registry System: (2-METHYL-PYRIDIN-3-YL)-METHANOL(56826-61-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 56826-61-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C5H4O2/c6-4-5-2-1-3-7-5/h1-4H

Upstream product

• 1721-26-2 ethyl 2-methyl nicotinate 
• 144-55-8 sodium hydrogencarbonate 
• 3222-56-8 2-methylnicotinic acid 
• 60032-57-7 2-methylnicotinaldehyde 
• 64987-16-2 (2-amino-thiazol-4-yl)-acetic acid methyl ester 
• 65719-09-7 methyl 2-methylnicotinate 
• 90643-19-9 2-methyl-1,4-dihydro-pyridine-3-carboxylic acid ethyl ester 

Downstream Products

• 98593-18-1 3-methoxymethyl-2-methyl-pyridine 
• 100710-48-3 3-benzyloximethyl-2-methyl-pyridine 
• 76915-53-2 3-(bromomethyl)-2-methylpyridine 
• 58539-77-8 2-methyl-3-chloromethylpyridine hydrochloride 
• 1027083-96-0 3-[2'-(4,4-Dimethyl-4,5-dihydro-oxazol-2-yl)-biphenyl-4-ylmethyl]-2-methyl-pyridine 
• 1026463-10-4 [2'-(4,4-Dimethyl-4,5-dihydro-oxazol-2-yl)-biphenyl-4-yl]-(2-methyl-pyridin-3-yl)-methanol 
• 1027192-23-9 3-{Chloro-[2'-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)-biphenyl-4-yl]-methyl}-2-methyl-pyridine 
• 1198424-07-5 (2-methylpyridin-3-yl)methyl 4-nitrophenyl carbonate 
• 1148147-39-0 methyl 4-({[(2-chloro-5-{[(2-methyl-3-pyridinyl)methyl]oxy}phenyl)carbonyl]amino}methyl)benzoate 
• 1421928-16-6 C₂₇H₃₁ClN₂O₂ 
• 1421928-19-9 C₃₀H₃₁N₃O 
• 1421928-23-5 C₃₁H₃₂N₂O₂ 
• 1421928-47-3 C₃₀H₂₉ClN₂O₂ 
• 1421928-59-7 ethyl 2-(4-((2-methylpyridin-3-yl)methoxy)phenyl)acetate 

Relevant articles and documents

Novel heterocyclic derivative capable of being used as SHP2 inhibitor

The invention relates to a novel heterocyclic derivative capable of being used as an SHP2 inhibitor, specifically relates to a compound shown by a formula I or pharmaceutically acceptable salts thereof, further relates to a use of the compound shown by the formula I or the pharmaceutically acceptable salts thereof and a pharmaceutical composition thereof in drug preparation, and particularly relates to a use in preparation of drugs for treatment, inhibition or prevention of diseases or discomforts mediated by SHP2 activity.

Lewis Acid-Catalyzed C(sp3)–C(sp3) Bond Forming Cyclization Reactions for the Synthesis of Tetrahydroprotoberberine Derivatives

An efficient Lewis acid-catalyzed C(sp3)–C(sp3) bond forming annulation reaction has been developed. This strategy serves as a new method for the facile synthesis of tetrahydro-5H-isoquinolino[2,1-g][1,6]naphthyridine derivatives. A wide range of 2-methylquinoline-3-carbaldehydes and 1,2,3,4-tetrahydroisoquinolines can be applied for this process to afford structurally diverse tetrahydroprotoberberine derivatives in excellent yields. (Figure presented.).

COMPOUNDS AND METHODS

The present invention relates to novel retinoid-related orphan receptor gamma (RORy) modulators and their use in the treatment of diseases mediated by RORy.