362489-59-6Relevant articles and documents
Efficient and practical asymmetric synthesis of 1-tert-butyl 3-methyl (3R,4R)-4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidine-1,3-dicarboxylate, a useful intermediate for the synthesis of nociceptin antagonists
Jona, Hideki,Shibata, Jun,Asai, Masanori,Goto, Yasuhiro,Arai, Sachie,Nakajima, Shigeru,Okamoto, Osamu,Kawamoto, Hiroshi,Iwasawa, Yoshikazu
experimental part, p. 2439 - 2446 (2010/03/03)
An efficient and practical asymmetric synthesis of 1-tert-butyl 3-methyl (3R,4R)-4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidine-1,3-dicarboxylate 1, a useful intermediate for the synthesis of nociceptin antagonists, has been developed. This method i
N-ureidoheterocycloalkyl-piperidines as modulators of chemokine receptor activity
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, (2008/06/13)
The present application describes modulators of CCR3 of formula (I): or pharmaceutically acceptable salt forms thereof, useful for the prevention of asthma and other allergic diseases.