362495-75-8

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 77184-95-3 (R)-2-benzylaziridine 
• 5267-64-1 (R)-2-amino-3-phenylpropanol 
• 140145-73-9 R-(+)-(3-Phenyl-2-tosylamido)propyl-tosylat 

Downstream Products

• 362495-84-9 [2S,4S,1'S,2'S]-(+)-N,2-dimethyl-5-phenyl-N-(2'-phenyl-2'-hydroxy-1'-methylethyl)-4-(p-toluenesulfonylamino)pentanamide 
• 362496-05-7 [2S,4S]-(+)-methyl 2-methyl-5-phenyl-4-(p-toluenesulfonylamino)pentanoate 
• 362495-95-2 [2S,4S]-(+)-2-methyl-5-phenyl-4-(p-toluenesulfonylamino)pentanoic acid 
• 1244040-49-0 C₃₈H₄₈N₄O₄S₂ 
• 1361969-56-3 C₂₁H₂₇NO₂SSi 
• 1361969-93-8 4-methyl-N-((R)-1-(pentyloxy)allyl)-N-((S)-1-phenylpent-4-yn-2-yl)benzenesulfonamide 
• 1361969-92-7 4-methyl-N-((S)-1-(pentyloxy)allyl)-N-((S)-1-phenylpent-4-yn-2-yl)benzenesulfonamide 
• 1361969-79-0 N-((S)-1-methoxyallyl)-4-methyl-N-((R)-1-phenyl-5-(trimethylsilyl)pent-4-yn-2-yl)benzenesulfonamide 
• 1361969-86-9 C₂₅H₃₃NO₃SSi 
• 1361969-85-8 4-methyl-N-((R)-1-(pentyloxy)allyl)-N-((R)-1-phenyl-5-(trimethylsilyl)pent-4-yn-2-yl)benzenesulfonamide 
• 1361969-78-9 4-methyl-N-((S)-1-(pentyloxy)allyl)-N-((R)-1-phenyl-5-(trimethylsilyl)pent-4-yn-2-yl)benzenesulfonamide 
• 1361970-07-1 (2R,6R)-2-benzyl-1-tosyl-6-vinylpiperidin-4-one 
• 1361970-06-0 (2R,6S)-2-benzyl-1-tosyl-6-vinylpiperidin-4-one 
• 1361970-04-8 (2R,6S)-2-benzyl-4-(pentyloxy)-1-tosyl-6-vinyl-1,2,3,6-tetrahydropyridine 

Relevant academic research and scientific papers

Fluoroalkanosulfonyl fluorides-mediated cyclodehydration of β-hydroxy sulfonamides and β-hydroxy thioamides to the corresponding aziridines and thiazolines

An efficient method for the fluoroalkanosulfonyl fluoride-induced cyclodehydration of β-hydroxy sulfonamides and β-hydroxy thioamides to the corresponding aziridines and thiazolines is reported. Mild reaction conditions, operational simplicity, and high y

Stereodefined N,O-acetals: Pd-catalyzed synthesis from homopropargylic amines and utility in the flexible synthesis of 2,6-substituted piperidines

We developed a conceptually new synthetic strategy which exploits the stereochemical information of labile acyclic N,O-acetals. The key to this strategy, chemo- and stereoselective synthesis of N,O-acetals, was achieved by the Pd-catalyzed addition of sulfonyl-protected homopropargylic amines to alkoxyallene. The N,O-acetals generated in this way were combined with Au-catalyzed cycloisomerization to give an access to 2,6-disubstituted piperidines with stereochemical flexibility.

A highly diastereo-and enantioselective copper(I)-catalyzed henry reaction using a bis(sulfonamide)-diamine ligand

A series of bis(sulfonamide)-diamine (BSDA) ligands were synthesized from commercially available chiral α-amino alcohols and diamines. The chiral BSDA ligand 3a, coordinated with Cu(I), catalyzes the enantioselective Henry reaction with excellent enantios

A highly effective bis(Sulfonamide)-diamine ligand: A unique chiral skeleton for the enantioselective Cu-catalyzed Henry reaction

(Figure Presented) A skeleton in the closet! As a unique chiral skeleton, the newly developed bis(sulfonamide)-diamine, which contains both diamine and bis(sulfonamide) moieties, was a highly effective ligand for the asymmetric Cu(OAc)2-catalyz

Investigation of a flexible enantiospecific approach to aziridines

(Chemical Equation Presented) A flexible approach to functionalized and enantioenriched aziridines has been developed from an intermediate aziridinylmethyl tosylate. This protocol features a Cu-catalyzed Grignard substitution reaction that allows a range of functionalized organic fragments to be incorporated. Moreover, a convenient one-pot procedure is outlined that allows the trityl group to be exchanged for a range of common N-protecting groups.

PREPARATION OF OPTICALLY ACTIVE 2-AMINOALKYLPHOSPHINIC AND PHOSPHONIC ACIDS

The reaction of sodium alkylphosphinates or sodium dialkylphosphonates with tosylamino tosylates of amino alcohols derived from 1-aminoalkylcarboxylic acids gives high yields of optically active 2-tosylaminoalkylphosphinic or phosphonic esters.