363134-35-4 Usage
Description
Benzaldehyde, 4-fluoro-3,5-dimethyl(9CI) is an organic compound characterized by the chemical formula C9H9FO. It presents itself as a pale yellow liquid, distinguished by a strong, sweet, and almond-like aroma. Benzaldehyde, 4-fluoro-3,5-dimethyl(9CI) is known for its versatile applications across various industries due to its unique properties.
Used in Food Industry:
Benzaldehyde, 4-fluoro-3,5-dimethyl(9CI) is used as a flavoring agent for enhancing the taste and aroma of various food products. Its almond-like scent makes it a popular choice for adding a distinct flavor profile to confectioneries, baked goods, and other edible items.
Used in Cosmetic and Perfume Industry:
In the cosmetic and perfume industry, Benzaldehyde, 4-fluoro-3,5-dimethyl(9CI) serves as a fragrance ingredient. Its sweet and pleasant odor contributes to the creation of various scents in perfumes, as well as adding a pleasant smell to skincare and beauty products.
Used in Pharmaceutical Industry:
Benzaldehyde, 4-fluoro-3,5-dimethyl(9CI) is utilized in the production of pharmaceuticals. Its chemical properties make it a valuable intermediate in the synthesis of various drugs, contributing to the development of new medications and therapies.
Used in Dye Industry:
Benzaldehyde, 4-fluoro-3,5-dimethyl(9CI) is also used in the dye industry for the production of different types of dyes. Its chemical structure allows it to be a key component in the creation of colorants used in textiles, printing, and other applications.
Used in Organic Compounds Production:
Benzaldehyde, 4-fluoro-3,5-dimethyl(9CI) is employed in the synthesis of other organic compounds. Its versatility in chemical reactions makes it a useful building block for the development of new organic molecules for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 363134-35-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,6,3,1,3 and 4 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 363134-35:
(8*3)+(7*6)+(6*3)+(5*1)+(4*3)+(3*4)+(2*3)+(1*5)=124
124 % 10 = 4
So 363134-35-4 is a valid CAS Registry Number.
363134-35-4Relevant articles and documents
Discovery of the First-in-Class Agonist-Based SOS1 PROTACs Effective in Human Cancer Cells Harboring Various KRAS Mutations
Cui, Rongrong,Diao, Xingxing,Fan, Zisheng,Jiang, Hualiang,Li, Yupeng,Liu, Chaoyi,Xu, Tianfeng,Zhang, Sulin,Zheng, Mingyue,Zhou, Chuan,Zhou, Guizhen,Zhou, Zehui
, p. 3923 - 3942 (2022/03/16)
Regulating SOS1 functions may result in targeted pan-KRAS therapies. Small-molecule SOS1 inhibitors showed promising anticancer potential, and the most advanced inhibitor BI 1701963 is currently under phase I clinical studies. SOS1 agonists provide new opportunities to treat cancer; however, the underlying mechanisms still warrant investigation. We here report the discovery of the first SOS1 PROTACs designed uniquely by connecting a VHL ligand to the reported SOS1 agonist, ensuring that the observed inhibitory activity results from degraders. The best compound 9d induced SOS1 degradation in various KRAS-driven cancer cells and displayed superior antiproliferation activity compared to the agonist itself. Tumor xenograft study clearly showed the promising antitumor potency of 9d against human lung cancer. This study provides good evidence of using agonists to design SOS1 PROTACs and demonstrates that targeted SOS1 degradation represents an effective therapeutic strategy for overcoming KRAS-driven cancers.
