99725-44-7

Usage

Uses

Used in Pharmaceutical Industry:
5-Bromo-2-fluoro-m-xylene is used as an intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs with specific therapeutic properties.
Used in Agrochemical Industry:
5-Bromo-2-fluoro-m-xylene is used as an intermediate in the synthesis of agrochemicals, contributing to the creation of compounds that can enhance crop protection and yield.
Used in Chemical Industry:
5-Bromo-2-fluoro-m-xylene is used as a building block for the production of a wide range of organic compounds, playing a crucial role in the synthesis of various specialty chemicals and materials.

InChI:InChI=1/C8H8BrF/c1-5-3-7(9)4-6(2)8(5)10/h3-4H,1-2H3

Upstream product

• 24596-19-8 4-bromo-2,6-dimethylphenylamine 

Downstream Products

• 1314888-30-6 1,3-bis-(tert-butoxycarbonylaminomethyl)-2-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene 
• 1314888-31-7 3,5-bis-(benzyloxycarbonylaminomethyl)-3',5'-bis-(tert-butoxycarbonylaminomethyl)-4,4'-difluorobiphenyl 
• 1314888-25-9 5-bromo-1,3-bis-(bromomethyl)-2-fluorobenzene 
• 1314888-27-1 1,3-bis-(aminomethyl)-5-bromo-2-fluorobenzene 
• 1314888-28-2 1,3-bis-(benzyloxycarbonylaminomethyl)-5-bromo-2-fluorobenzene 
• 1314888-29-3 1,3-bis-(tert-butoxycarbonylaminomethyl)-5-bromo-2-fluorobenzene 
• 342636-66-2 (4-fluoro-3,5-dimethylphenyl)boronic acid 
• 1840-27-3 4-fluoro-3,5-dimethyl-benzenamine 
• 1043889-82-2 (R)-2-(4-fluoro-3,5-dimethylphenylamino)hexanoic acid hydroxyamide 
• 1043890-86-3 (R)-2-(4-fluoro-3,5-dimethylphenylamino)hexanoic acid tert-butoxyamide 
• 1147894-98-1 2-(4-fluoro-3,5-dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 886501-82-2 5-(bromomethyl)-2-fluoro-1,3-dimethylbenzene 

Relevant academic research and scientific papers

Spiro-substituted azacycles as neurokinin antagonists

Disclosed are spiro-substituted azacycles of formula I are tachykinin receptor antagonists useful in the treatment of inflammatory diseases, pain or migraine, and asthma. In particular compounds of formula I are shown to be neurokinin antagonists.

SPIRO-SUBSTITUTED AZACYCLES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY

The present invention is directed to spiro-substituted azacycles of the Formula 1: STR1 (wherein R 1, l, m, Q, W, X, Y, and Z are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-1, CCR-2, CCR-2A, CCR-2B, CCR-3, CCR-4, CCR-5, CXCR-3, and/or CXCR-4.

3-Hydroxy-3-methylglutaryl-coenzyme A Reductase Inhibitors. 3. 7-(3,5-Disubstituted -2-yl)-3,5-dihydroxy-6-heptenoic Acids and Their Lactone Derivatives

The syntheses of a series of 7-(3,5-disubstituted -2-yl)-3,5-dihydroxy-6-heptenoic acids and their lactones are reported.Intrinsic 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitory activity is enhanced markedly when the biphenyl mo