363136-59-8 Usage
Uses
1. Used in Pharmaceutical Industry:
1-Bromo-4-[(2-methylpropane)sulfinyl]benzene is used as a key intermediate for the preparation of geminally substituted cyanoethylpyrazolopyridones. These compounds act as Janus kinase (JAK) inhibitors, which are important for the treatment of various inflammatory and autoimmune diseases.
a) As an intermediate for the synthesis of JAK inhibitors, 1-Bromo-4-[(2-methylpropane)sulfinyl]benzene plays a crucial role in the development of medications for rheumatoid arthritis, a chronic autoimmune disorder that causes inflammation and damage to the joints.
b) 1-Bromo-4-[(2-methylpropane)sulfinyl]benzene is also used in the preparation of drugs for asthma treatment, a common respiratory condition characterized by inflammation and narrowing of the airways, leading to difficulty in breathing.
c) In the context of chronic obstructive pulmonary disease (COPD), 1-Bromo-4-[(2-methylpropane)sulfinyl]benzene contributes to the development of JAK inhibitors that can help manage the symptoms and reduce the frequency of exacerbations.
d) Furthermore, 1-Bromo-4-[(2-methylpropane)sulfinyl]benzene is utilized in the synthesis of JAK inhibitors for cancer treatment, as these inhibitors can help regulate the signaling pathways involved in cell growth and proliferation, potentially leading to the suppression of tumor development.
Check Digit Verification of cas no
The CAS Registry Mumber 363136-59-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,6,3,1,3 and 6 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 363136-59:
(8*3)+(7*6)+(6*3)+(5*1)+(4*3)+(3*6)+(2*5)+(1*9)=138
138 % 10 = 8
So 363136-59-8 is a valid CAS Registry Number.
