36314-51-9

Usage

Uses

1,2-Ditetradecyl-sn-glycerol is used in the synthesis of cationic cardiolipin analogs.

Upstream product

• 112-71-0 1-Bromotetradecane 
• 128229-34-5 (4R,5R)-4,5-Bis-((R)-1,2-bis-tetradecyloxy-ethyl)-2,2-dimethyl-[1,3]dioxolane 
• 90126-97-9 (2R,3S,4S,5R)-1,2,5,6-Tetrakis-tetradecyloxy-hexane-3,4-diol 
• 36314-50-8 (R)-1,2-bis-tetradecyloxy-3-O-benzylpropane 
• 128229-35-6 (R)-2,3-Bis-tetradecyloxy-propionaldehyde 

Downstream Products

• 81281-37-0 3-O-(3,6-Di-O-acetyl-2,4-di-O-benzyl-α-D-mannopyranosyl)-1,2-di-O-tetradecyl-sn-glycerol 
• 85648-57-3 (2R,3R,4S,5S,6R)-2-(2,3-Bis-tetradecyloxy-propoxy)-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol 
• 81281-22-3 3-O-α-D-Mannopyranosyl-1,2-di-O-tetradecyl-sn-glycerol 
• 81281-22-3 3-O-α-D-Galactopyranosyl-1,2-di-O-tetradecyl-sn-glycerol 
• 81281-22-3 3-O-α-D-Glucopyranosyl-1,2-di-O-tetradecyl-sn-glycerol 
• 81281-22-3 3-O-β-D-Galactopyranosyl-1,2-di-O-tetradecyl-sn-glycerol 
• 81281-22-3 3-O-β-D-Glucopyranosyl-1,2-di-O-tetradecyl-sn-glycerol 
• 81294-88-4 3-O-(3,4,6-Tri-O-benzyl-α-D-mannopyranosyl)-1,2-di-O-n-tetradecyl-sn-glycerol 
• 81281-38-1 3-O-(2,4-Di-O-benzyl-α-D-mannopyranosyl)-1,2-di-O-tetradecyl-sn-glycerol 
• 123001-17-2 3-O-(6-O-α-D-Mannopyranosyl-α-D-mannopyranosyl)-1,2-di-O-n-tetradecyl-sn-glycerol 
• 680220-11-5 2-O-benzyl-1,3-bis[(1,2-di-O-myristyl-sn-glycero-3)-phosphoryl]glycerol di(2-cyanoethyl) ester 

Relevant academic research and scientific papers

Synthesis of cationic cardiolipin analogues

An approach was developed to synthesize a new class of cationic cardiolipin analogues containing two quaternary ammonium groups with tetra alkyl groups retaining "glycerol" moiety, the central core of the molecule. Cationic cardiolipin analogues were modified via introduction of either two or four oxyethylene groups to enhance the solubility in polar solvents. These newly synthesized cationic cardiolipin analogues can be applied to a broad range of drug delivery systems such as transfection reagents.

Synthesis of novel cationic cardiolipin analogues for the optimal delivery of therapeutic agents

A novel approach was developed to synthesize cardiolipin analogues containing two quaternary ammonium groups with tetraalkyl chain retaining 'glycerol' moiety, the central core of the molecule. The analogues were synthesized with or without spacer and/or

4'-desmethyl nucleoside analogs, and oligomers thereof

Tetrahydrofuranyl compounds are provided that are functionalized to include pendant conjugate groups, and which are useful in diagnostic assays and as research reagents. Novel intermediates for the synthesis of the compounds are also provided.

Synthesis of 3-O-Glycosyl-1,2-di-O-tetradecyl-sn-glycerol

Ten diether type monoglycosyl and glycobiosyl glycerolipids, including 3-O-(4-O-β-D-galactopyranosyl-β-D-glucopyranosyl)-1,2-di-O-n-tetradecyl-sn-glycerol, a synthetic analogue of lactosyl ceramide, were synthesized and their stereochemistry was assigned