36336-80-8

Usage

General Description

The chemical 3-[4-(1-Methylethyl)phenyl]-1-phenyl-2-propen-1-one is a compound with the molecular formula C18H18O. It is a ketone with a phenyl group, a 1-phenyl-2-propen-1-one moiety, and a 4-(1-methylethyl)phenyl substituent. 3-[4-(1-Methylethyl)phenyl]-1-phenyl-2-propen-1-one is commonly used in organic synthesis and pharmaceutical research, as well as in the production of various industrial chemicals. Its unique structure and properties make it a valuable intermediate in the synthesis of complex organic molecules. Additionally, it has been studied for its potential biological activities and pharmacological properties.

InChI:InChI=1/C18H18O/c1-14(2)16-11-8-15(9-12-16)10-13-18(19)17-6-4-3-5-7-17/h3-14H,1-2H3

Upstream product

• 98-85-1 1-Phenylethanol 
• 536-60-7 cuminol 
• 536-74-3 phenylacetylene 
• 122-03-2 (4-isopropylbenzaldehyde) 
• 98-86-2 acetophenone 

Downstream Products

• 58774-38-2 1-phenyl-3-(4-(isopropyl)phenyl)propan-1-one 
• 31535-70-3 1-benzyl-3-(2-oxo-2-phenylethyl)indolin-2-one 
• 1438487-88-7 (5-(4-isopropylphenyl)-2-(2-nitrophenyl)-2H-1,2,3-triazol-4-yl)(phenyl)methanone 
• 39615-70-8 3-(4-Isopropyl-phenyl)-4,4,6-trimethyl-1-phenyl-heptane-1,5-dione 

Relevant academic research and scientific papers

1-Formyl-3-phenyl-5-(4-isopropylphenyl)-2-pyrazoline: Synthesis, characterization, antimicrobial activity and DFT studies

The structure of 1-formyl-3-phenyl-5-(4-isopropylphenyl)-2-pyrazoline synthesized as single crystal was investigated by FTIR, NMR, XRD. Experimental data were complemented by quantum mechanical calculations. XRD data show that the compound crystallizes in

Co-N-C Catalyst for C-C Coupling Reactions: On the Catalytic Performance and Active Sites

C-C bond-forming reactions are important in chemistry for construction of complex large molecules from readily available simple substrates. However, they usually involve the employment of organic halides and suffer from toxic or environmental issues. We report an efficient and environmentally benign methodology-aerobic oxidative cross-coupling of primary and secondary alcohols-to directly produce α,β-unsaturated ketones that are key intermediates for synthesis of agrochemical, pharmaceutical, and other fine chemicals. A noble-metal-free Co-N-C catalyst, derived from pyrolysis of cobalt-phenanthroline complexes on a mesoporous carbon support, is developed toward the target reactions and shows high catalytic activity (turnover frequency of 3.8 s-1 based on Co single atoms, surpassing the state of art in the literature), good recyclability, and wide applicability to diverse substrates (28 examples). The active sites in the Co-N-C catalyst are proposed to be Co single atoms bonded with N within graphitic sheets.

An improved iron-mediated synthesis of N-2-aryl substituted 1,2,3-triazoles

Treatment of various chalcones and sodium azide in the presence of catalytic amounts of commercially available iron oxide nanoparticles, followed by the addition of aryl halides afforded N-2-arylated 1,2,3-triazoles in very good yields. This tandem three-

Graphite oxide as an auto-tandem oxidation-hydration-aldol coupling catalyst

Graphite oxide (GO) was found to function as an auto-tandem oxidation-hydration-aldol coupling catalyst for the formation of chalcones in a single reaction vessel. Various alkynes or alcohols were hydrated or oxidized in situ to their corresponding methyl ketones or aldehydes, respectively, which underwent a subsequent Claisen-Schmidt condensation. Each of the aforementioned reactions proceeded in the absence of metals (confirmed by inductively coupled plasma mass spectrometry, ICP-MS) and afforded a range of chalcone products in good to excellent yields from commercially available starting materials.

Gaseous [CnH2n+1 + . . . 1,3-Diphenylpropane] ion/neutral complexes containing alkyl cations of different acidities and hydride ion affinities

Gaseous ion/neutral (I/N) complexes [R+ . . . C 6H5CH2CH2CH2C 6H5] with R = t-C4H9+, s-C4H9+ and s-C