36357-49-0Relevant articles and documents
Synthesis of a C3-symmetric tris-imine via dynamic covalent bond formation between a trialdehyde and a triamine
Nakada, Keiko,Kondo, Seiya,Matsumoto, Yoshiteru,Yamanaka, Masamichi
supporting information, p. 4612 - 4616 (2017/11/15)
Dynamic covalent chemistry is an effective technique for the preparation of complex organic compounds. We succeeded in synthesizing a cage-shaped compound through the aggregation of two types of functional molecules. More specifically, a tris-imine 5 was quantitatively obtained by reacting a C3-symmetric trialdehyde 1 with a triamine 4 in acetonitrile in the presence of a trifluoroacetic acid catalyst. We also achieved the synthesis of the corresponding triamine 9 and the acetylated derivative 10 through reduction of the tris-imine C[dbnd]N double bonds and subsequent acetylation.
