363619-54-9Relevant articles and documents
Synthesis of β-D-Galp-(1 →4)-α-D-Manp methanephosphonate, a substrate analogue for the elongating α-D-mannosyl phosphate transferase in the Leishmania
Borodkin, Vladimir S,Ferguson, Michael A.J,Nikolaev, Andrei V
, p. 5305 - 5308 (2007/10/03)
An isosteric C-glycoside phosphono analogue of dec-9-enyl β-D-galactopyranosyl-(1 →4)-α-D-mannopyranosyl phosphate was synthesised and showed high biological activity in the Leishmania MPT assay. A one-step Horner-Emmons/Michael reaction was developed for the stereoselective preparation of α-D-mannosyl methanephosphonate derivatives.