36375-80-1

Basic information

• Product Name: 2,3,4,5,6-pentafluoro-N-o-tolylbenzenamine
• Synonyms: 2,3,4,5,6-pentafluoro-N-o-tolylbenzenamine
• CAS NO: 36375-80-1
• Molecular Weight: 273.205
• Mol File: 36375-80-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2,3,4,5,6-pentafluoro-N-o-tolylbenzenamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,4,5,6-pentafluoro-N-o-tolylbenzenamine(36375-80-1)
• EPA Substance Registry System: 2,3,4,5,6-pentafluoro-N-o-tolylbenzenamine(36375-80-1)

Safety Data

• Hazardous Substances Data: 36375-80-1(Hazardous Substances Data)

Upstream product

• 392-56-3 Hexafluorobenzene 
• 95-53-4 o-toluidine 
• 1423-15-0 perfluorophenyl azide 

Relevant articles and documents

Effective, transition metal free and selective C-F activation under mild conditions

A simple and effective aromatic nucleophilic monosubstitution reaction for the synthesis of aromatic amines via selective C-F bond cleavage of various fluoroarenes (mono-, di-, tri-, tetra-, penta- and perfluorobenzene) with primary and secondary aromatic amines under transition metal free conditions is demonstrated. The reaction conditions were investigated thoroughly for a wide range of fluoroarene substrates bearing different numbers of fluorine atoms, and the results showed that the solvent and reaction temperature are very crucial for the successful substitution reactions. The established methods enabled the formation of nonfluorinated and partially fluorinated aromatic amines in good to excellent yields. Several functional groups were tolerated under the optimized conditions.

Remarkable catalysis of intersystem crossing of singlet (Pentafluorophenyl)nitrene

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