36386-85-3

Usage

Uses

Used in Pharmaceutical Industry:
2H-1,2,3-Triazole-4-carbonyl chloride, 2-phenyl(9CI) is used as a building block for the synthesis of various biologically active compounds, contributing to the development of new pharmaceuticals with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 2H-1,2,3-Triazole-4-carbonyl chloride, 2-phenyl(9CI) is utilized as a key intermediate in the creation of agrochemicals, helping to develop new products for crop protection and enhancement of agricultural yields.
Used in Organic Synthesis:
2H-1,2,3-Triazole-4-carbonyl chloride, 2-phenyl(9CI) is employed as a reagent in organic synthesis for the introduction of the 2-phenyl-1,2,3-triazole moiety into a variety of compounds, facilitating the creation of new chemical entities with diverse applications.

Upstream product

• 13306-99-5 2-phenyl-2H-[1,2,3]triazole-4-carboxylic acid 

Downstream Products

• 855609-86-8 2-diazo-1-(2-phenyl-2H-[1,2,3]triazol-4-yl)-ethanone 
• 89522-57-6 N-(5-tetrazolyl)-2-phenyl-1,2,3-triazole-4-carboxamide 
• 1167427-14-6 5-methyl-2-(2-phenyl-1,2,3-triazol-4-yl)-1,3,4-oxadiazole 
• 221445-87-0 5-phenyl-2-(2-phenyl-1,2,3-triazol-4-yl)-1,3,4-oxadiazole 
• 1167427-19-1 tris[2-{2-(2-phenyl-1,2,3-triazol-4-yl)-1,3,4-oxadiazol-5-yl}ethyl]nitromethane 
• 1167427-16-8 2,5-bis(2-phenyl-1,2,3-triazol-4-yl)-1,3,4-oxadiazole 
• 1335130-20-5 1-benzyl-4-[N-(2-phenyl-1,2,3-triazol-4-yl)carbamoyl]oxymethyl-1,2,3-triazole 
• 1335130-21-6 1-(1H-1,2,4-triazol-3-yl)-4-[N-(2-phenyl-1,2,3-triazol-4-yl)carbamoyl]oxymethyl-1,2,3-triazole 
• 1335129-93-5 1,2,5-oxadiazole-3,4-diylbismethylene bis(2-phenyl-2H-1,2,3-triazol-4-yl)carbamate 
• 1335130-22-7 N,N'-bis(2-phenyl-2H-1,2,3-triazol-4-yl)urea 
• 1335130-15-8 2-phenyl-1,2,3-triazole-4-carboxylic acid azide 
• 1378894-45-1 N-(2-phenyl-2H-1,2,3-triazol-4-yl)-N'-(1H-1,2,4-triazol-3-yl)urea 
• 1378894-46-2 N-(2-phenyl-2H-1,2,3-triazol-4-yl)-N'-(4H-1,2,4-triazol-4-yl)urea 
• 1378894-48-4 N-(1,4-diphenyl-1H-1,2,3-triazol-5-yl)-N'-(2-phenyl-2H-1,2,3-triazol-4-yl)urea 

Relevant academic research and scientific papers

Synthesis of polynuclear azoles linked through carbamate and urea bridges

Polynuclear azoles linked through carbamate and urea fragments were synthesized by reactions of the corresponding azolecarboxylic acid azides with heterocyclic alcohols and amines. Pleiades Publishing, Ltd., 2012.

The curtius reaction in the synthesis of noncondensed polynuclear azoles

Polynuclear noncondensed systems in which the azole rings are bound by urethane or carbamide fragments have been synthesized by the reaction of azole carboxylic acid azides with heterocyclic alcohols.

Synthesis of branched polynuclear 1,3,4-oxadiazoles

The reaction of 5-substituted mono-and polytetrazoles with heterocyclic acid chlorides and trifluoroacetic acid anhydride gave branched polynuclear 1,3,4-oxadiazole systems.

Human β3-adrenergic receptor agonists containing 1,2,3-triazole-substituted benzenesulfonamides

Compounds containing a 1,2,3-triazole-substituted benzenesulfonamide were prepared and found to be potent and selective human β3-adrenergic receptor agonists. The most interesting compound, trifluoromethylbenzyl analogue 12e (β3 ECs

Synthesis of Some 4-Substituted-2-(o-halogenophenyl)-1,2,3-triazoles

Mesoladehyde 1,3-dioxime was treated with either 2,4,6-trichlorophenyl- (a), o-fluorophenyl- (b), or o-bromophenyl- (c) hydrazine to give corresponding mesoaldehyde 1,3-dioxime-2-halogenophenylhydrazones (1a,b,c).The latter were O-acetylated with acetic anhydride, and cyclized to triazole 4-oximes (3b,c) or triazole 4-O-acetyloximes (6a,b,c) with cesium carbonate, then converted to nitrile (7a,b,c) by refluxing with acetic anhydride followed by pyrolysis, or to aldehydes (4a,b,c) by hydrolysis.The nitriles (7a,b,c) were also converted to acids (9a,b,c), esters (10a,b,c), amides (8a,c), an alcohol (11a), and an amine (12a).In addition , tetrazoles of two types were prepared.The first (13d,e) were obtained from the acid chlorides by the action of 5-aminotetrazole, whereas the second (14f) was produced from the respective nitrile by the action of ammonium azide.