36388-09-7

Usage

Uses

Used in Pharmaceutical Industry:
1-(dipropylamino)propan-2-ol is used as a pharmaceutical intermediate for the synthesis of various drugs. Its unique structure allows it to act as a building block in the development of new medications, contributing to the advancement of pharmaceutical research and drug discovery.
Used in Chemical Research and Production:
1-(dipropylamino)propan-2-ol is used as a solvent in chemical research and production. Its ability to dissolve a wide range of substances makes it a valuable tool in various chemical processes, facilitating reactions and improving the efficiency of production.
Used as a Corrosion Inhibitor:
1-(dipropylamino)propan-2-ol is used as a corrosion inhibitor in various industrial applications. Its chemical properties enable it to protect metal surfaces from corrosion, extending the lifespan of equipment and infrastructure, and reducing maintenance costs.
Safety Precautions:
It is important to handle and store 1-(dipropylamino)propan-2-ol with care, as it can be harmful if ingested, inhaled, or absorbed through the skin. Additionally, it may cause irritation to the eyes and respiratory system. Proper safety measures, such as wearing protective gear and following storage guidelines, should be taken to minimize potential risks.

InChI:InChI=1/C9H21NO/c1-4-6-10(7-5-2)8-9(3)11/h9,11H,4-8H2,1-3H3

Upstream product

• 5666-19-3 allyl-dipropyl-amine 
• 142-84-7 di-n-propylamine 
• 75-56-9 methyloxirane 
• 107-08-4 1-iodo-propane 
• 78-96-6 3-amino-2-propanol 
• 7664-93-9 sulfuric acid 
• 102-69-2 tri-n-propylamine 

Relevant academic research and scientific papers

Platinum-Catalyzed, Terminal-Selective C(sp3)-H Oxidation of Aliphatic Amines

This Communication describes the terminal-selective, Pt-catalyzed C(sp3)-H oxidation of aliphatic amines without the requirement for directing groups. CuCl2 is employed as a stoichiometric oxidant, and the reactions proceed in high yield at Pt loadings as low as 1 mol%. These transformations are conducted in the presence of sulfuric acid, which reacts with the amine substrates in situ to form ammonium salts. We propose that protonation of the amine serves at least three important roles: (i) it renders the substrates soluble in the aqueous reaction medium; (ii) it limits binding of the amine nitrogen to Pt or Cu; and (iii) it electronically deactivates the C-H bonds proximal to the nitrogen center. We demonstrate that this strategy is effective for the terminal-selective C(sp3)-H oxidation of a variety of primary, secondary, and tertiary amines.

Hydrophobic amplification of noncovalent organocatalysis

The effects of hydrogen-bonding organocatalysts and water for the acceleration of epoxide openings with a variety of nucleophiles are additive and lead to excellent yields of the catalyzed reactions in water. The Royal Society of Chemistry 2006.

Effect of branching in alkylgroups of tertiary amines on their performance as catalysts in the high pressure promoted Bylis-Hillman reaction

Receptors 1 were tested as catalysts for the high pressure promoted Baylis-Hillman reaction. Surprisingly most of the compounds were found to be catalytically inactive. With model compounds (simple acyclic tertiary amines) it could be shown that tertiary amines with branches at their α-carbon atoms show a remarkable decreased activity. It is proposed that the branches prevent attack of the lone pair of the amine on the double bond of the alkene. This explains why only receptors without this feature are catalytically active.