36401-55-5Relevant academic research and scientific papers
The structural properties of 5-methyl-2-phenyl-2H-1,2,3-triazole-4- carboxylic acid and chromogenic mechanism on its rhodamine B derivatives to Hg2+ ions
Li, Jianling,Ding, Guohua,Niu, Yanyan,Wu, Luyong,Feng, Huajie,He, Wenying
, p. 127 - 135 (2018)
5-Methyl-2-phenyl-2H-1,2,3-triazole-4-carboxylic acid (MPTC), a newly synthesized compound, was explored to study the structural properties and theoretical spectra by using GaussView5.0 program package and the time dependent density functional theory (TD
Preparation of novel antibacterial agents. Replacement of the central aromatic ring with heterocycles
Li, Jianke,Wakefield, Brian D.,Ruble, J. Craig,Stiff, Cory M.,Romero, Donna L.,Marotti, Keith R.,Sweeney, Michael T.,Zurenko, Gary E.,Rohrer, Douglas C.,Thorarensen, Atli
, p. 2347 - 2350 (2008/12/21)
Discovery of novel antibacterial agents is a significant challenge. We have recently reported on our discovery of novel antibacterial agents in which we have rapidly optimized potency utilizing a parallel chemistry approach. These advanced leads suffer from high affinity for human serum albumin (HSA). In an effort to decrease the affinity for HSA we have prepared a series of heterocyclic analogs, which retained antibacterial activity and demonstrated reduced affinity for HSA.
HETEROARYL SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES
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Page/Page column 23, (2008/06/13)
The invention relates to substituted cyclohexyl-1,4-diamine derivatives, a method for the production thereof, medicaments containing these compounds, and to the use of substituted cyclohexyl-1,4-diamine derivatives for producing medicaments.
