36402-34-3

Upstream product

• 96-09-3 styrene oxide 
• 75-77-4 chloro-trimethyl-silane 
• 1450-14-2 1,1,1,2,2,2-hexamethyldisilane 
• 1674-30-2 1-phenyl-2-chloroethanol 

Downstream Products

• 20372-72-9 (2-chloro-1-fluoroethyl)benzene 

Relevant academic research and scientific papers

Palladium-catalyzed silylation of alcohols with hexamethyldisilane

The combination of hexamethyldisilane and a catalytic amount of [PdCl(η3-C3H5)]2-PPh 3 was found to be effective for the trimethylsilylation of alcohols, where both of the two trimethylsilyl groups of hexamethyldisilane were transferred to alcohols without coproduction of any stoichiometric amount of byproduct but H2. The Royal Society of Chemistry 2006.

1,2-Ferrocenediylazaphosphinines 2: A new class of nucleophilic catalysts for ring-opening of epoxides

1,2-Ferrocenediylazaphosphinines (1a-c) have been successfully employed as a new class of nucleophilic catalysts for ring-opening of a range of epoxides, their catalytic efficiency in terms of regioselectivity as well as chemical yield comparing well with the existing catalysts in the literature. In contrast, low enantiomeric excesses have been obtained from the reactions of meso-epoxides catalyzed by (R)-1.

SODIUM BROMIDE CATALYSED REGIOSELECTIVE CLEAVAGE OF OXIRANES WITH CHLOROTRIMETHYLSILANE

Sodium bromide efficiently catalyses the regioselective cleavage of oxiranes with chlorotrimethylsilane to the corresponding O-silyiated chlorohydrins in excellent yield.

ACTION D'HALOGENOSILANES SUR LES OXYDES DE VINYL-2 FURANNE, DE STYRENE ET DE BUTENE-1. ETUDE DES REGIO ISOMERES PAR RMN-(13)C

(13)C-NMR shows that the regiochemistry of the reaction of a halosilane Me3SiX (X=Cl, Br) on a dissymetric epoxide depends of R: RCHXCH2OSiMe3 (a, R=2-Fu, Ph) or RCHOSiMe3CH2X (b, R=Et, b>a).

Formation et stabilite des carbenoides monohalogenes β-ethers

The β-alkoxy monohalogenated carbenoids, C6H5CH(OSiMe3)CHXLi, can be obtained by bromine-lithium exchange from the corresponding bromohaloether in the presence of s-butllithium in a mixture of THF/ether/pentane at -130 deg C.The stability of the carbenoid (α-elimination and β-elimination) is described and discussed.

Cobalt(II) Chloride Catalysed Regioselective Cleavage of Oxiranes with Chlorotrimethylsilane

Oxiranes can be cleaved regioselectively with chlorotrimethylsilane in presence of cobalt(II) chloride to the corresponding O-silylated vicinal chlorohydrins in excellent yields.

NUCLEOPHILIC CATALYSIS IN THE INSERTION OF SILICON HALIDES INTO OXIRANES: A SYNTHESIS OF O-PROTECTED VICINAL HALOHYDRINS

Silicon halides in the presence of nucleophilic catalysts react with epoxides to form O-protected vicinal halohydrins with enhanched regioselectivity.