364043-73-2Relevant articles and documents
Influence of 2-substituent on the activity of imidazo[1,2-a] pyridine derivatives against human cytomegalovirus
Mavel, Sylvie,Renou, Jean-Louis,Galtier, Christophe,Allouchi, Hassan,Snoeck, Robert,Andrei, Graciella,De Clercq, Erik,Balzarini, Jan,Gueiffier, Alain
, p. 941 - 946 (2002)
The synthesis of various 2-substituted imidazo[1,2-a]pyridine bearing a thioether side chain in position 3 was reported. The new compounds were characterized by 1H and 13C NMR spectra. A conformational study was obtained by X-ray crystallographic analysis for 2-biphen-4-ylimidazopyridine 7. The antiviral activity against human cytomegalovirus (HCMV) was investigated. It was strongly influenced by the nature of C-2 substituent. Copyright