40086-66-6

Basic information

• Product Name: 2-bromo-1-pyridin-2-yl-ethanone
• Synonyms: 2-(Bromoacetyl)pyridine;2-Bromo-1-(pyridin-2-yl)ethan-1-one;Ethanone, 2-broMo-1-(2-pyridinyl)-;2-bromo-1-(2-pyridinyl)Ethanone;2-Bromo-1-(pyridin-2-yl);2-Bromo-1-pyridin-2-ylethanon
• CAS NO: 40086-66-6
• Molecular Formula: C₇H₆BrNO
• Molecular Weight: 200.03
• Mol File: 40086-66-6.mol
• Article Data: 26

Chemical Properties

• Boiling Point: 249.1 °C at 760 mmHg
• Flash Point: 104.5 °C
• Appearance: /
• Density: 1.57 g/cm³
• Vapor Pressure: 2.64E-06mmHg at 25°C
• Refractive Index: 1.638
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 2.06±0.10(Predicted)
• CAS DataBase Reference: 2-bromo-1-pyridin-2-yl-ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-1-pyridin-2-yl-ethanone(40086-66-6)
• EPA Substance Registry System: 2-bromo-1-pyridin-2-yl-ethanone(40086-66-6)

Safety Data

• Hazardous Substances Data: 40086-66-6(Hazardous Substances Data)

Usage

General Description

"2-Bromo-1-pyridin-2-yl-ethanone" is a chemical compound with a molecular formula of C8H8BrNO. It is also known by its systematic name, 1-(2-bromophenyl)-2-pyridinyl-ethanone. 2-bromo-1-pyridin-2-yl-ethanone falls under the category of organobromides and organoheterocyclic compounds. It is a brominated derivative of ethanone with an additional pyridin-2-yl group. Specific properties such as its melting point, boiling point, density, and solubility are not readily available due to this compound's less common usage. It's commonly used in chemical and pharmaceutical research for the synthesis of other compounds, but its safety, reactivity, and environmental impacts are not well-studied and therefore, handling this compound requires caution.

InChI:InChI=1/C7H7BrN2O/c8-5-7(11)10-6-3-1-2-4-9-6/h1-4H,5H2,(H,9,10,11)

Upstream product

• 1122-62-9 2-acetylpyridine 
• 26510-52-1 ethyl 2-pyridylcarbonylacetate 
• 6940-57-4 2-acetyl-6-methylpyridine 
• 100-69-6 2-vinylpyridine 

Downstream Products

• 2881-34-7 2,2'-(thiazole-2,4-diyl)bis(pyridine) 
• 150223-59-9 4-phenyl-2-<4-(pyridin-2-yl)thiazol-2-yl>pyridine 
• 150223-67-9 4-(4-nitrobenzyl)-2-<4-(pyridin-2-yl)thiazol-2-yl>pyridine 
• 866220-09-9 2,23-bis-(4-pyridin-2-yl-thiazol-2-yl)-6,7,9,10,12,13,15,16,18,19-decahydro-5,8,11,14,17,20-hexaoxa-1,24-diaza-dibenzo[a,c]cycloeicosene 
• 894768-47-9 NC₅H₄C₃HNS((C₅H₂N(OC₂H₄)2OCH₂)2H) 
• 364043-76-5 7-methyl-3-nitroso-2-pyridin-2-yl-imidazo[1,2-a]pyridine 
• 150223-60-2 4-phenyl-2-<4-(pyridin-2-yl)thiazol-2-yl>pyridine N,N'-dioxide 
• 150223-68-0 4-(4-nitrobenzyl)-2-<4-(pyridin-2-yl)thiazol-2-yl>pyridine N,N'-dioxide 
• 4013-71-2 pyridine-2-carbonyl azide 
• 521268-46-2 (2S)-1-{[2-(4-Pyridin-2-yl-thiazol-2-ylamino)-ethylamino]-acetyl}-pyrrolidine-2-carbonitrile 
• 453568-45-1 2-(3-iodophenyl)-4-(pyridin-2-yl)-1,3-thiazole 
• 194282-25-2 Ni((C₆H₅)2PCH₂CH₂P(C₆H₅)2)(S₂C₂HC₅H₄N) 
• 30235-26-8 4-pyridin-2-yl-thiazol-2-ylamine 
• 1443221-42-8 4-methoxy-N-[4-phenyl-5-(pyridine-2-carbonyl)thiazol-2-yl]benzamide 

Relevant articles and documents

Base-Catalyzed Intramolecular Defluorination/O-Arylation Reaction for the Synthesis of 3-Fluoro-1,4-oxathiine 4,4-Dioxide

A novel process involving base-catalyzed intramolecular defluorination/O-arylation of readily available α-fluoro-β-one-sulfones was realized and provided a series of 3-fluoro-1,4-oxathiine 4,4-dioxide derivatives in good to excellent yields. Unlike traditional defluorination reactions with stoichiometric base as the deacid reagent, this process is triggered by a catalytic amount of base (TMG: tetramethylguanidine) and molecular sieves serve as both an adsorbent to remove HF acid and an activator to assist C-F bond cleavage.

SUBSTITUTED PROPANAMIDES AS INHIBITORS OF NUCLEASES

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Antibacterial synergist, preparation method and uses thereof

The present invention relates to an antibacterial synergist, a preparation method and uses thereof, and specifically discloses a compound represented by a formula (I) and having antibacterial synergyactivity, or an optical isomer, a cis-trans isomer or a pharmaceutically acceptable salt thereof, and a preparation method thereof. The present invention further discloses a medical composition containing the compound, and uses thereof. According to the present invention, the compound can effectively enhance the antibacterial activity of polymyxin B against Acinetobacter baumannii and Klebsiella pneumoniae, and can be used for the antibacterial treatment of pathogenic bacteria insensitive to polymyxin or having low bacterial inhibition activity. The formula (I) is defined in the specification.