364053-03-2Relevant academic research and scientific papers
Microwave assisted synthesis of 4-thiazolidinones and its 5-arylidene derivatives: Screening of antimicrobial activity with various microorganisms
Upadhyay, Apoorva,Srivastava,Srivastava,Upadhyay, Navneeta
, p. 1025 - 1031 (2012/03/26)
Several new ethyl(isonicotinamid-4-yl)acetate (1), 2-(isonicotinamid-4-yl) acetohydrazide (2), 2-(isonicotinamid-4-yl)acetylhydrazino arylidenes (3a-j), 2-aryl-3-[(isonicotinamid-4-yl)acetamido]-4-oxo-1,3-thiazolidines (4a-j) and 5-arylidene-2-aryl-3-[(isonicotinamid-4-yl)acetamido]-4-oxo-1,3-thiazolidines (5a-j) have been synthesized. The structures of all the newly synthesized compounds were confirmed by IR, 1H NMR, 13C NMR, FAB-Mass spectra and by microanalytical data. Compounds 4a-j and 5a-j have been screened for their antibacterial and antifungal activity against some selected microorganisms.
