36413-97-5

Upstream product

• 93-35-6 7-hydroxy-2H-chromen-2-one 
• 117431-88-6 7-<<3-(α,α-dimethyl-3-isoxazolemethanol-5-yl)-2-butyl>oxy>-2H-1-benzopyran-2-one 
• 117431-87-5 5<3-hydroxy-1-methyl-1-propyl>-α,α-dimethyl-3-isoxazolemethanol 
• 121693-79-6 (E)-tert-butyldimethyl-((3-methylpent-2-en-4-yn-1-yl)oxy)silane 
• 117431-89-7 7-<<(E)-6-amino-7-hydroxy-3,7-dimethyl-4-oxo-5-octenyl>oxy>-2H-1-benzopyran-2-one 
• 117431-85-3 5<(E)-3-(t-butyldimethylsilyloxy)-1-methyl-1-propenyl>-α,α-dimethyl-3-isoxazolemethanol 

Relevant academic research and scientific papers

ISOXAZOLES-MEDIATED SYNTHESIS OF GEIPARVARIN AND DIHYDROGEIPARVARIN

A new synthesis of geiparvarin 1 and its dihydroderivative 2, two naturally occuring antitumor agents, possessing the 3(2H)-furanone ring system central structural feature, is described.The synthetic design is based on the use of suitably substituted isoxazole derivatives, the heterocyclic ring acting as masked 1,3-diketone moiety.