364355-93-1

Basic information

• Product Name: BenzenesulfonaMide, N-[4-[4-aMino-7-(4-oxocyclohexyl)-7H-pyrrolo[2,3-d]pyriMidin-5-yl]-2-fluorophenyl]-2,3-dichloro-
• Synonyms: BenzenesulfonaMide, N-[4-[4-aMino-7-(4-oxocyclohexyl)-7H-pyrrolo[2,3-d]pyriMidin-5-yl]-2-fluorophenyl]-2,3-dichloro-;N1-[4-[4-Amino-7-(4-oxocyclohexyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-fluorophenyl]-2,3-dichloro-1-benzenesulfonamide
• CAS NO: 364355-93-1
• Molecular Formula: C₂₄H₂₀Cl₂FN₅O₃S
• Molecular Weight: 548
• Mol File: 364355-93-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Density: 1.62
• CAS DataBase Reference: BenzenesulfonaMide, N-[4-[4-aMino-7-(4-oxocyclohexyl)-7H-pyrrolo[2,3-d]pyriMidin-5-yl]-2-fluorophenyl]-2,3-dichloro-(CAS DataBase Reference)
• NIST Chemistry Reference: BenzenesulfonaMide, N-[4-[4-aMino-7-(4-oxocyclohexyl)-7H-pyrrolo[2,3-d]pyriMidin-5-yl]-2-fluorophenyl]-2,3-dichloro-(364355-93-1)
• EPA Substance Registry System: BenzenesulfonaMide, N-[4-[4-aMino-7-(4-oxocyclohexyl)-7H-pyrrolo[2,3-d]pyriMidin-5-yl]-2-fluorophenyl]-2,3-dichloro-(364355-93-1)

Safety Data

• Hazardous Substances Data: 364355-93-1(Hazardous Substances Data)

Upstream product

• 364355-99-7 4-[4-amino-5-(4-amino-3-chlorophenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]-1-cyclohexanone 
• 82417-45-6 dichlorobenzenesulfonyl chloride 

Relevant articles and documents

Pyrrolopyrimidines as therapeutic agents

Chemical compounds having structural formula I and physiologically acceptable salts and metabolites thereof, are inhibitors of serine/threonine and tyrosine kinase activity. Several of the kinases, whose activity is inhibited by these chemical compounds, are involved in immunologic, hyperproliferative, or angiogenic processes. Thus, these chemical compounds can ameliorate disease states where angiogenesis or endothelial cell hyperproliferation is a factor. These compounds can be used to treat cancer and hyper proliferative disorders, rheumatiod arthritis, disorders of the immune system, trasplant refections and imflammatory disorders.