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N-(2-((2-nitrophenyl)sulfonamido)ethyl)acetamide is a complex organic chemical compound with the molecular formula C10H12N4O5S. It is a derivative of acetamide, featuring a sulfonamide group attached to a 2-nitrophenyl ring. N-(2-((2-nitrophenyl)sulfonamido)ethyl)acetamide is characterized by its yellow crystalline appearance and is soluble in water. It is primarily used in the synthesis of various pharmaceuticals and chemical intermediates due to its unique structure and reactivity. The presence of the nitro group and sulfonamide functionality makes it a potentially valuable building block in the development of new drugs and other chemical products.

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  • 3645-19-0 Structure
  • Basic information

    1. Product Name: N-(2-((2-nitrophenyl)sulfonamido)ethyl)acetamide
    2. Synonyms: N-(2-((2-nitrophenyl)sulfonamido)ethyl)acetamide
    3. CAS NO:3645-19-0
    4. Molecular Formula:
    5. Molecular Weight: 287.296
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 3645-19-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: N-(2-((2-nitrophenyl)sulfonamido)ethyl)acetamide(CAS DataBase Reference)
    10. NIST Chemistry Reference: N-(2-((2-nitrophenyl)sulfonamido)ethyl)acetamide(3645-19-0)
    11. EPA Substance Registry System: N-(2-((2-nitrophenyl)sulfonamido)ethyl)acetamide(3645-19-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 3645-19-0(Hazardous Substances Data)

3645-19-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 3645-19-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,6,4 and 5 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 3645-19:
(6*3)+(5*6)+(4*4)+(3*5)+(2*1)+(1*9)=90
90 % 10 = 0
So 3645-19-0 is a valid CAS Registry Number.

3645-19-0Downstream Products

3645-19-0Relevant articles and documents

Direct β- and γ-C(sp3)?H Alkynylation of Free Carboxylic Acids**

Ghiringhelli, Francesca,Ghosh, Kiron Kumar,Uttry, Alexander,van Gemmeren, Manuel

, p. 23127 - 23131 (2020)

In this study we report the identification of a novel class of ligands for palladium-catalyzed C(sp3)?H activation that enables the direct alkynylation of free carboxylic acid substrates. In contrast to previous synthetic methods, no introduction/removal of an exogenous directing group is required. A broad scope of acids including both α-quaternary and challenging α-non-quaternary can be used as substrates. Additionally, the alkynylation in the distal γ-position is reported. Finally, this study encompasses preliminary findings on an enantioselective variant of the title transformation as well as synthetic applications of the products obtained.

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