365282-18-4

Upstream product

• 31938-11-1 O-tritylhydroxylamine 
• 463300-56-3 4-benzylsulfanyl-2-((4-methoxy-benzenesulonyl)-{[(pyridin-3-ylmethyl)-carbamoyl]-methyl}-amino)-butyric acid 
• 365281-96-5 (2-oxotetrahydro-thiophen-3-ylamino)-acetic acid tert-butyl ester 
• 463300-55-2 4-benzylsulfanyl-2-((4-methoxy-benzenesulfonyl)-{[(pyridin-3-ylmethyl)-carbamoyl]methyl}-amino)-butyric acid methyl ester 
• 237423-49-3 4-benzylsulfanyl-2-[tert-butoxycarbonylmethyl-(4-methoxy-benzenesulfonyl)-amino]-butyric acid methyl ester 
• 237423-50-6 4-benzylsulfanyl-2-[carboxymethyl-(4-methoxy-benzenesulfonyl)-amino]-butyric acid methyl ester 
• 257933-90-7 [(4-methoxy-benzenesulfonyl)-(2-oxo-tetrahydrothiophen-3-yl)-amino]-acetic acid tert-butyl ester 

Relevant academic research and scientific papers

N-aryl sulfonyl homocysteine hydroxamate inhibitors of matrix metalloproteinases: Further probing of the S1, S1′, and S2′ pockets

A series of N-arylsulfonyl S-alkyl homocysteine hydroxamic acids were synthesized with variations in three subsites corresponding to P1, P1′, and P2′. Enzyme assays with a variety of MMPs revealed activity at the low nanomolar level.