365413-00-9

Basic information

• Product Name: 2-(1-(tert-butoxycarbonyl)piperidin-4-yl)thiazole-4-carboxylic acid
• Synonyms: 2-(1-(tert-butoxycarbonyl)piperidin-4-yl)thiazole-4-carboxylic acid
• CAS NO: 365413-00-9
• Molecular Formula: C₁₄H₂₀N₂O₄S
• Molecular Weight: 312.3846
• Mol File: 365413-00-9.mol
• Article Data: 20

Chemical Properties

• Melting Point: 162-166℃
• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-(1-(tert-butoxycarbonyl)piperidin-4-yl)thiazole-4-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1-(tert-butoxycarbonyl)piperidin-4-yl)thiazole-4-carboxylic acid(365413-00-9)
• EPA Substance Registry System: 2-(1-(tert-butoxycarbonyl)piperidin-4-yl)thiazole-4-carboxylic acid(365413-00-9)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 22-26-36/37/39
• Hazardous Substances Data: 365413-00-9(Hazardous Substances Data)

Usage

General Description

2-(1-(tert-butoxycarbonyl)piperidin-4-yl)thiazole-4-carboxylic acid is a chemical compound with a molecular formula C15H21N3O4S. It is a thiazole derivative that contains a piperidine ring with a tert-butoxycarbonyl functional group attached. 2-(1-(tert-butoxycarbonyl)piperidin-4-yl)thiazole-4-carboxylic acid has potential pharmaceutical applications, particularly in the development of new drugs for treating various diseases. It is also used in chemical research and as a building block for the synthesis of other compounds. The unique structure of 2-(1-(tert-butoxycarbonyl)piperidin-4-yl)thiazole-4-carboxylic acid makes it a valuable and versatile molecule in medicinal and chemical sciences.

Upstream product

• 91419-48-6 4-carbamoyl-piperidine-1-carboxylic acid tert-butyl ester 
• 922516-53-8 ethyl 2-(1-(tert-butoxycarbonyl)-1,2,3,6-tetrahydropyridin-4-yl)thiazole-4-carboxylate 
• 137076-22-3 tert butyl 4-formylpiperidine-1-carboxylate 
• 139290-70-3 tert-butyl 4-(methoxy(methyl)carbamoyl)piperidine-1-carboxylate 
• 84358-13-4 N-[(tert-butoxy)carbonyl]piperidine-4-carboxylic acid 
• 881197-94-0 4-(4-ethoxycarbonyl-4,5-dihydrothiazol-2-yl)-piperidine-1-carboxylic acid tert-butyl ester 
• 1192878-45-7 4-(2-ethoxycarbonyl-2-oxo-ethylsulanylcarbonimidoyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 214834-18-1 tert-butyl 4-carbamothioylpiperidine-1-carboxylate 
• 365413-31-6 ethyl 2-(1-(tert-butoxy carbonyl )piperidin-4-yl)thiazole-4-carboxylate 

Downstream Products

• 1416725-86-4 3-chloro-2-hydroxy-N-(2-piperidin-4-yl-thiazol-4-yl)-benzamide 
• 1416521-66-8 N-(2-{1-[2-(3,5-bis-difluoromethyl-pyrazol-1-yl)-acetyl]-piperidin-4-yl}-thiazol-4-yl)-3-chloro-2-hydroxy-benzamide 
• 1416725-85-3 4-[4-(3-chloro-2-hydroxy-benzoylamino)-thiazol-2-yl]-piperidine-1-carboxylic acid tert-butyl ester 
• 1361190-38-6 4-[4-(3-{1-[4-(2-amino-pyrimidin-5-yl)-phenyl]-cyclobutyl}-[1,2,4]oxadiazol-5-yl)-thiazol-2-yl]-piperidine-1-carboxylic acid tert-butyl ester 
• 1361188-98-8 5-(4-{1-[5-(2-piperidin-4-yl-thiazol-4-yl)-[1,2,4]oxadiazol-3-yl]-cyclobutyl}-phenyl)pyrimidin-2-ylamine 
• 1345958-33-9 (Z)-2-[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]-1-{4-[4-(2-cyclohexyl-N-methoxyethanimidoyl)-1,3-thiazol-2-yl]piperidin-1-yl}ethanone 
• 1345958-30-6 2-[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]-1-{4-[4-(cyclohexylacetyl)-1,3-thiazol-2-yl]piperidin-1-yl}ethanone 
• 1345958-31-7 N-(5-chloro-2-methylphenyl)-4-[4-(cyclohexylacetyl)-1,3-thiazol-2-yl]piperidine-1-carboxamide 
• 1345958-91-9 4-[4-(cyclohexylacetyl)-1,3-thiazol-2-yl]piperidinium chloride 
• 1345958-90-8 tert-butyl 4-[4-(cyclohexylacetyl)-1,3-thiazol-2-yl]piperidine-1-carboxylate 
• 1296887-12-1 Cyclohexyl 2-{1-[(2,5-dimethylphenyl)carbamoyl]piperidin-4-yl}-1,3-thiazole-4-carboxylate 

Relevant articles and documents

A novel class of potent NF-κB signaling inhibitors

A novel class of NF-κB pathway signaling inhibitors was discovered by virtual screening, medicinal chemistry, and QSAR analysis. An initial set of compounds inhibited NF-κB signaling in a whole cell reporter gene assay in the micro-molar range. Activity was improved step by step by medicinal chemistry to yield nano-molar signaling inhibitors.

NOVEL FUNGIDAL HETEROCYCLIC COMPOUNDS

The present invention relates to a compound selected from Formula (I) and its salts, metal complexes, N-oxides, isomers, and polymorphs: Formula (I) wherein E, Z, R3, n, G, J & Q have the meaning as defined in the description.

A class of nitrogen-containing heterocyclic thiazole derivative and its preparation and use

The invention provides a nitrogen heterocyclic ring thiazole derivative, a preparation method and applications thereof, and relates to isothiazole oxime ether compounds, which have a chemical construction general formula shown in the description. The inve