365432-18-4

Upstream product

• 537-55-3 N-acetyl-L-tyrosine 
• 365432-14-0 N-acetyl-L-tyrosine allyl ester 
• 365432-22-0 N-methyl-N-(4-chlorobutyl)phosphoramidic dichloride 

Downstream Products

• 365432-00-4 N-methyl-N-(4-chlorobutyl) O-(5-nitrofuryl-2-methyl) O-(4-((S)-2-acetylamino-2-carboxyethyl))phenyl phosphoramidate 
• 365431-88-5 (S)-2-Acetylamino-3-{4-[[(4-chloro-butyl)-methyl-amino]-(5-nitro-furan-2-ylmethoxy)-phosphoryloxy]-phenyl}-propionic acid allyl ester 

Relevant academic research and scientific papers

Design and synthesis of phosphotyrosine peptidomimetic prodrugs

A novel approach to the intracellular delivery of aryl phosphates has been developed that utilizes a phosphoramidate-based prodrug approach. The prodrugs contain an ester group that undergoes reductive activation intracellularly with concomitant expulsion