365555-15-3Relevant academic research and scientific papers
Synthesis of the ABC- and D-ring systems of the indole alkaloid ambiguine G
Chandra, Aroop,Viswanathan, Rajesh,Johnston, Jeffrey N.
, p. 5027 - 5029 (2008/03/28)
A glycine Schiff base Michael addition is used in sequence with free radical-mediated aryl amination to ultimately arrive at the ambiguine G ABC-tricycle convergently. Additionally, thermal Diels-Alder cycloaddition of β-chloromethacrolein with Cohen's di
Structure-activity relationship of linear peptide Bu-His-DPhe-Arg-Trp-Gly-NH2 at the human melanocortin-1 and -4 receptors: Histidine substitution
Cheung, Adrian Wai-Hing,Danho, Waleed,Swistok, Joseph,Qi, Lida,Kurylko, Grazyna,Rowan, Karen,Yeon, Mitch,Franco, Lucia,Chu, Xin-Jie,Chen, Li,Yagaloff, Keith
, p. 133 - 137 (2007/10/03)
Systematic substitution of His6 residue using non-selective hMC4R pentapeptide agonist (Bu-His6-DPhe7-Arg8-Trp9-Gly 10-NH2) as the template led to the identification of Bu-Atcsu
Selective cyclic peptides with melanocortin-4 receptor (MC4-R) agonist activity
-
, (2008/06/13)
Peptides cyclized via disulfide or lactam bridges having melanocortin-4 receptor (MC4-R) agonist activity useful for treatment of obesity.
Selective linear peptides with melanocortin-4 receptor (MC4-R) agonist activity
-
, (2008/06/13)
Peptides of formulae I, II and III selectively activate melanocortin-4 (MC-4) receptor activity.
