132095-53-5 Usage
Description
5-Bromo-2-tetralone is an organic compound with the molecular formula C10H9BrO. It is a derivative of tetralone, featuring a bromine atom at the 5th position and a ketone group at the 2nd position. 5-Bromo-2-tetralone is known for its potential applications in various fields due to its unique chemical structure and properties.
Uses
Used in Pharmaceutical Industry:
5-Bromo-2-tetralone is used as a reagent for the preparation of 2-aminotetralins, which are known for their high affinity and selectivity for the dopamine D3 receptor. This application is particularly relevant in the development of drugs targeting the dopaminergic system, which plays a crucial role in various neurological and psychiatric disorders, such as schizophrenia, Parkinson's disease, and addiction.
Check Digit Verification of cas no
The CAS Registry Mumber 132095-53-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,2,0,9 and 5 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 132095-53:
(8*1)+(7*3)+(6*2)+(5*0)+(4*9)+(3*5)+(2*5)+(1*3)=105
105 % 10 = 5
So 132095-53-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H9BrO/c11-10-3-1-2-7-6-8(12)4-5-9(7)10/h1-3H,4-6H2
132095-53-5Relevant articles and documents
Synthesis of the ABC- and D-ring systems of the indole alkaloid ambiguine G
Chandra, Aroop,Viswanathan, Rajesh,Johnston, Jeffrey N.
, p. 5027 - 5029 (2007)
A glycine Schiff base Michael addition is used in sequence with free radical-mediated aryl amination to ultimately arrive at the ambiguine G ABC-tricycle convergently. Additionally, thermal Diels-Alder cycloaddition of β-chloromethacrolein with Cohen's di
COMPOUNDS AND METHODS FOR MODULATING SEROTONIN RECEPTORS IN THE PERIPHERY
-
, (2016/12/07)
This invention relates to, in part, compositions and methods that are useful for, inter alia, the treatment of various diseases, including those linked to binding at a serotonin receptor in the Gl tract.
Structure-activity relationship of linear peptide Bu-His-DPhe-Arg-Trp-Gly-NH2 at the human melanocortin-1 and -4 receptors: Histidine substitution
Cheung, Adrian Wai-Hing,Danho, Waleed,Swistok, Joseph,Qi, Lida,Kurylko, Grazyna,Rowan, Karen,Yeon, Mitch,Franco, Lucia,Chu, Xin-Jie,Chen, Li,Yagaloff, Keith
, p. 133 - 137 (2007/10/03)
Systematic substitution of His6 residue using non-selective hMC4R pentapeptide agonist (Bu-His6-DPhe7-Arg8-Trp9-Gly 10-NH2) as the template led to the identification of Bu-Atcsu