36556-33-9

Usage

Uses

Used in Pharmaceutical Industry:
1,3,5-trichloro-2-fluoro-benzene is used as an intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the formation of complex molecular structures required in medicinal chemistry.
Used in Agrochemical Industry:
1,3,5-trichloro-2-fluoro-benzene is utilized as an intermediate in the production of agrochemicals, playing a role in the development of substances that can protect crops and enhance agricultural yields.
Used in Organic Synthesis:
1,3,5-trichloro-2-fluoro-benzene is employed as a reagent in organic synthesis, facilitating the creation of a range of organic compounds due to its reactive functional groups.
Used in Chemical Reactions as a Solvent:
It serves as a solvent in various chemical reactions, providing a medium for the reactions to occur and potentially influencing the reaction rate or product distribution.
Safety Note:
1,3,5-trichloro-2-fluoro-benzene can be harmful if inhaled or ingested and may cause irritation to the skin and eyes. It is crucial to handle this chemical with care and follow proper safety protocols during its use.

InChI:InChI=1/C6H2Cl3F/c7-3-1-4(8)6(10)5(9)2-3/h1-2H

Upstream product

• 634-93-5 2,4,6-trichloroaniline 
• 18708-70-8 2,4,6-trichloronitrobenzene 

Downstream Products

• 4780-58-9 2,3,4,6-Tetrachlor-N-methyl-anilin 
• 4877-74-1 2,3,4,6-Tetrachlor-thiophenol 
• 319-95-9 2,3,4,6-Tetrachlorofluorobenzene 
• 94897-81-1 4,5,6-trichloro-2-(2,4,6-trichlorophenoxy)phenol 
• 94888-09-2 4,6-dichloro-2-(2,4,6-trichlorophenoxy)phenol 
• 4815-62-7 2.4.6-Trichlor-1-fluor-3-nitro-benzol 
• 50903-31-6 5-Chloro-2-(2,4,6-trichloro-phenoxy)-phenol 

Relevant academic research and scientific papers

Preparation process of fluorine substituted aromatic compound

A preparation process of a fluorine substituted aromatic compound comprising reacting an alkali metal or alkali earth metal salt of an aromatic compound having a hydroxy group with an organic fluorinating agent is disclosed. As a representative fluorinating agent, a bis-dialkylamino-difluoromethane compound, for example, 2,2′-difluoro-1,3-dimethylimidazolidine, is exemplified. According to the process, an industrially useful fluorinated aromatic compound, for example, a fluorobenzene, a fluorine substituted benzophenone, a fluorine substituted diarylsulfone can be prepared with ease in economy without specific equipment.

Methylhexamethylenetetramine fluoride dihydrate: A new fluorodenitration reagent

Methylhexamethylenetetramine fluoride dihydrate has been prepared by conventional methods. It is moderately soluble in polar aprotic solvents, and shows good thermal stability, enabling it to be dried. The reagent is capable of converting activated nitroaromatics to the corresponding fluoroaromatics, with a high selectivity to monofluorodenitration being observed with some polysubstituted aromatics.

PREPARATION OF AROMATIC FLUORIDES VIA DIAZOTIZATION AND PHOTOCHEMICALLY INDUCED FLUORO-DEDIAZONIATION OF AROMATIC AMINES IN ANHYDROUS HYDROGEN FLUORIDE - ORGANIC BASE SOLUTIONS

Fluoro-dediazoniation of aromatic diazonium ions, produced by the diazotization of the corresponding aromatic amines with NaNO2 in anhydrous hydrogen fluorides (AHF) - organic base solutions, was accelerated photochemically to afford Ar-F efficiently in AHF - organic base solutions in situ.