36556-47-5

Basic information

• Product Name: 2,3-DIFLUOROCHLOROBENZENE
• Synonyms: 2,3-DIFLUOROCHLOROBENZENE;1-Chloro-2,3-difluorobenzene;Benzene, 1-chloro-2,3-difluoro-
• CAS NO: 36556-47-5
• Molecular Formula: C₆H₃ClF₂
• Molecular Weight: 148.5378264
• Product Categories: Miscellaneous
• Mol File: 36556-47-5.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 137.083 °C at 760 mmHg
• Flash Point: 34.567 °C
• Appearance: /
• Density: 1.353 g/cm³
• Vapor Pressure: 8.88mmHg at 25°C
• Refractive Index: 1.478
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2,3-DIFLUOROCHLOROBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-DIFLUOROCHLOROBENZENE(36556-47-5)
• EPA Substance Registry System: 2,3-DIFLUOROCHLOROBENZENE(36556-47-5)

Safety Data

• Hazard Codes: F
• Hazardous Substances Data: 36556-47-5(Hazardous Substances Data)

Usage

General Description

2,3-Difluorochlorobenzene is a halogenated aromatic organic compound. As suggested by its name, its chemical structure comprises a benzene ring substituted by two fluoride atoms and one chloride atom. It is used as a reagent in various chemical reactions and synthesis processes due to its active sites that can initiate a reaction. This colorless liquid has a relatively low boiling point and moderately high melting point, making it useful in several industrial applications. Like many other organic compounds, it should be appropriately managed and handled due to its potential flammability and toxicity. It is not widely found in natural conditions and is primarily produced in laboratory settings.

InChI:InChI=1/C6H3ClF2/c7-4-2-1-3-5(8)6(4)9/h1-3H

Upstream product

• 360-47-4 3-(1-chloro-vinyl)-1,1,2,2-tetrafluoro-cyclobutane 
• 356-96-7 1-chloro-2,2,3,3-tetrafluoro-1-vinyl-cyclobutane 
• 2646-83-5 3,3,4,4-tetrafluorocyclohexene 
• 356-77-4 1,1,2,2-tetrafluoro-3-vinylcyclobutane 
• 100703-93-3 1-chloro-5,5,6,6-tetrafluorocyclohex-1-ene 
• 87-61-6 1,2,3-trichlorobenzene 

Downstream Products

• 367-11-3 ortho-difluorobenzene 
• 1116681-98-1 2-(4-chloro-2,3-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 1437779-87-7 2-(3-chloro-4,5-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 1160573-23-8 4-chloro-2,3-difluorobenzaldehyde 
• 1073339-17-9 2-(2,3-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 53780-44-2 1-Chloro-2,3-difluoro-5-nitrobenzene 
• 771-69-7 2,3,4-trifluoronitrobenzene 
• 169468-80-8 1-chloro-2,3-difluoro-4-nitrobenzene 
• 169468-83-1 2-chloro-3,4-difluoro-1-nitrobenzene 
• 1805115-08-5 2-fluoro-3-chloro-4-nitrophenol 
• 82419-40-7 2-fluoro-3-chloro-6-nitrophenol 

Relevant articles and documents

Three-step regioselective synthesis of 2,3-difluorohalobenzenes using tetrafluoroethylene and buta-1,3-diene as starting building blocks

The gas-phase copyrolysis of tetrafluoroethylene and buta-1,3-diene in a flow tube reactor at 490–510 °C gives 3,3,4,4-tetrafluorocyclohex-1-ene, which is selectively converted to 1-bromo- or 1-chloro-2,3-difluorobenzene via intermediate steps of halogenation and dehydrohalogenation.

Method for producing tetrakis ( fluoroaryl) borate-magnesium compound

Fluoroaryl magnesium halide is reacted with a boron compound so that a molar ratio of the fluoroaryl magnesium halide to the boron compound is not less than 3.0 and not more than 3.7, so as to produce a tetrakis (fluoroaryl) borate·magnesium compound. With this method, there occurs no hydrogen fluoride which corrodes a producing apparatus and requires troublesome waste water treatment.

AROMATIC FLUORINE CHEMISTRY. PART 5. PREPARATION OF 2,6-DIFLUOROANILINE AND 1,2-DIFLUOROBENZENE

The preparation of 2,6-difluoroaniline and 1,2-difluorobenzene from 1,2,3-trichlorobenzene is described.An isomeric mixture of 1-chloro-2,3-difluorobenzene and 2-chloro-1,3-difluorobenzene is obtained from KF exchange on 1,2,3-trichlorobenzene.Selective dechlorination of 1-chloro-2,3-difluorobenzene with H2 and Pd/C catalyst gives 1,2-difluorobenzene. 2,6-difluoroaniline is obtained via ammonolysis of 2-chloro-1,3-difluorobenzene.