36556-47-5

Usage

Uses

Used in Chemical Synthesis:
2,3-Difluorochlorobenzene is used as a reagent in chemical synthesis processes for its active sites that can initiate reactions. Its unique structure allows for the creation of a wide range of compounds, making it a valuable component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Industrial Applications:
2,3-Difluorochlorobenzene is employed in various industrial applications due to its properties, such as its low boiling point and moderate melting point. These characteristics make it suitable for use in the production of materials with specific thermal and chemical properties, such as polymers and resins.
Used in Laboratory Research:
2,3-Difluorochlorobenzene is utilized in laboratory research as a starting material for the preparation of various organic compounds. Its reactivity and structural features make it an important tool in the development of new chemical entities and the study of reaction mechanisms.
Used in Material Science:
2,3-Difluorochlorobenzene is used as a building block in the development of new materials with specific properties, such as improved thermal stability, chemical resistance, or electronic characteristics. Its incorporation into the molecular structure of these materials can lead to enhanced performance in various applications, including electronics, coatings, and adhesives.

InChI:InChI=1/C6H3ClF2/c7-4-2-1-3-5(8)6(4)9/h1-3H

Upstream product

• 87-61-6 1,2,3-trichlorobenzene 
• 360-47-4 3-(1-chloro-vinyl)-1,1,2,2-tetrafluoro-cyclobutane 
• 356-96-7 1-chloro-2,2,3,3-tetrafluoro-1-vinyl-cyclobutane 
• 100703-93-3 1-chloro-5,5,6,6-tetrafluorocyclohex-1-ene 
• 356-77-4 1,1,2,2-tetrafluoro-3-vinylcyclobutane 
• 2646-83-5 3,3,4,4-tetrafluorocyclohexene 

Downstream Products

• 367-11-3 ortho-difluorobenzene 
• 1805115-08-5 2-fluoro-3-chloro-4-nitrophenol 
• 82419-40-7 2-fluoro-3-chloro-6-nitrophenol 
• 53780-44-2 1-Chloro-2,3-difluoro-5-nitrobenzene 
• 169468-80-8 1-chloro-2,3-difluoro-4-nitrobenzene 
• 169468-83-1 2-chloro-3,4-difluoro-1-nitrobenzene 
• 771-69-7 2,3,4-trifluoronitrobenzene 
• 1116681-98-1 2-(4-chloro-2,3-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 1073339-17-9 2-(2,3-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 1160573-23-8 4-chloro-2,3-difluorobenzaldehyde 
• 1437779-87-7 2-(3-chloro-4,5-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 

Relevant academic research and scientific papers

Three-step regioselective synthesis of 2,3-difluorohalobenzenes using tetrafluoroethylene and buta-1,3-diene as starting building blocks

The gas-phase copyrolysis of tetrafluoroethylene and buta-1,3-diene in a flow tube reactor at 490–510 °C gives 3,3,4,4-tetrafluorocyclohex-1-ene, which is selectively converted to 1-bromo- or 1-chloro-2,3-difluorobenzene via intermediate steps of halogenation and dehydrohalogenation.

Synthesis of fluorinated halonitrobenzenes and halonitrophenols using tetrafluoroethylene and buta-1,3-dienes as starting building blocks

The gas-phase copyrolysis of tetrafluoroethylene with buta-1,3-diene in a flow reactor at 495–505 °C produces 3,3,4,4-tetrafluorocyclohex-1-ene, which selectively converted to 1,2-difluorobenzene or 1-chloro-2,3-difluorobenzene. The latter can be converted to 2-chloro-3,4-difluoronitrobenzene, 2,3,4-trifluoronitrobenzene, 2,3-difluoro-6-nitrophenol, or 2-chloro-3-fluoro-4-nitrophenol via nitration, fluorodechlorination, and hydrolysis reactions.

Method for producing tetrakis ( fluoroaryl) borate-magnesium compound

Fluoroaryl magnesium halide is reacted with a boron compound so that a molar ratio of the fluoroaryl magnesium halide to the boron compound is not less than 3.0 and not more than 3.7, so as to produce a tetrakis (fluoroaryl) borate·magnesium compound. With this method, there occurs no hydrogen fluoride which corrodes a producing apparatus and requires troublesome waste water treatment.

AROMATIC FLUORINE CHEMISTRY. PART 5. PREPARATION OF 2,6-DIFLUOROANILINE AND 1,2-DIFLUOROBENZENE

The preparation of 2,6-difluoroaniline and 1,2-difluorobenzene from 1,2,3-trichlorobenzene is described.An isomeric mixture of 1-chloro-2,3-difluorobenzene and 2-chloro-1,3-difluorobenzene is obtained from KF exchange on 1,2,3-trichlorobenzene.Selective dechlorination of 1-chloro-2,3-difluorobenzene with H2 and Pd/C catalyst gives 1,2-difluorobenzene. 2,6-difluoroaniline is obtained via ammonolysis of 2-chloro-1,3-difluorobenzene.

Preparation of substituted fluorobenzenes

Substituted fluorobenzenes are produced by pyrolyzing vinylfluorocyclobutanes at a temperature of 250°-450° C. in the presence of activated carbon or certain metal oxides or mixtures of metal oxides.