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365565-85-1

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365565-85-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 365565-85-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,6,5,5,6 and 5 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 365565-85:
(8*3)+(7*6)+(6*5)+(5*5)+(4*6)+(3*5)+(2*8)+(1*5)=181
181 % 10 = 1
So 365565-85-1 is a valid CAS Registry Number.

365565-85-1Downstream Products

365565-85-1Relevant academic research and scientific papers

Novel morpholine ketone analogs as potent histamine H3 receptor inverse agonists with wake activity

Sundar, Babu G.,Bailey, Thomas R.,Dunn, Derek,Hostetler, Greg A.,Chatterjee, Sankar,Bacon, Edward R.,Yue, Christoph,Schweizer, Dominique,Aimone, Lisa D.,Gruner, John A.,Lyons, Jacquelyn,Raddatz, Rita,Lesur, Brigitte

, p. 1546 - 1549 (2012/04/04)

Structure-activity relationship on a novel ketone class of H3R antagonists/inverse agonists is disclosed. Compound 4 showed excellent target potency, selectivity and brain penetration. Evaluation of antagonist 4 in the rat EEG/EMG model demonstrated robust wake activity thereby establishing preclinical proof of concept.

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