365572-09-4

Basic information

• Product Name: 1-(2-Bromoethyl)-4-(1-methylethoxy)benzene
• Synonyms: 1-(2-Bromoethyl)-4-(1-methylethoxy)benzene
• CAS NO: 365572-09-4
• Molecular Formula: C₁₁H₁₅BrO
• Molecular Weight: 243.1402
• Mol File: 365572-09-4.mol

Chemical Properties

• Boiling Point: 281.821 °C at 760 mmHg
• Flash Point: 111.522 °C
• Appearance: /
• Density: 1.261 g/cm³
• CAS DataBase Reference: 1-(2-Bromoethyl)-4-(1-methylethoxy)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-Bromoethyl)-4-(1-methylethoxy)benzene(365572-09-4)
• EPA Substance Registry System: 1-(2-Bromoethyl)-4-(1-methylethoxy)benzene(365572-09-4)

Safety Data

• Hazardous Substances Data: 365572-09-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
1-(2-Bromoethyl)-4-(1-methylethoxy)benzene is used as an intermediate in the pharmaceutical industry for the synthesis of various drugs. Its unique chemical structure allows it to serve as a building block in the creation of complex medicinal compounds, contributing to the development of novel treatments for a range of health conditions.
Used in Agrochemical Production:
In the agrochemical industry, 1-(2-Bromoethyl)-4-(1-methylethoxy)benzene is utilized as an intermediate in the production of different agrochemicals. Its role in this sector is vital for the development of innovative products aimed at enhancing crop protection and improving agricultural yields.
Used as a Solvent:
1-(2-Bromoethyl)-4-(1-methylethoxy)benzene may also be employed as a solvent in certain chemical processes. Its solvent properties can facilitate various reactions, making it a valuable component in the chemical industry.
Used as a Reagent:
Furthermore, 1-(2-Bromoethyl)-4-(1-methylethoxy)benzene can be used as a reagent in chemical reactions, where it can help drive specific transformations or serve as a catalyst to increase the efficiency of a process.

Upstream product

• 4074-51-5 1-(4-isopropoxyphenyl)ethan-1-one 
• 14140-15-9 4-(2-bromoethyl)phenol 
• 67-63-0 isopropyl alcohol 
• 365572-08-3 2-Bromo-1-[4-(1-methylethoxy)phenyl]ethanone 

Downstream Products

• 380375-80-4 4-(1-methylethoxy)benzeneethanthiol 
• 1147863-94-2 5-(2-(4-isopropoxyphenyl)ethyl)-2,8-dimethyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole 
• 1508310-71-1 4-(2-iodoethyl)phenyl 1-methylethyl ether 
• 1508310-72-2 1-(2-{4-[(1-methylethyl)oxy]phenyl}ethyl)-5-nitro-1H-indole 
• 1508310-73-3 1-(2-{4-[(1-methylethyl)oxy]phenyl}ethyl)-1H-indol-5-amine 
• 1508310-50-6 2-[4-(ethylsulfonyl)phenyl]-N-[1-(2-{4-[(1-methylethyl)oxy]phenyl}ethyl)-1H-indol-5-yl]acetamide 
• 380375-82-6 1-bromo-5-methoxy-4-(1-methylethoxy)-2-[[2-[4-(1-methylethoxy)phenyl]ethylsulfonyl]methyl]benzene 
• 380375-81-5 1-bromo-5-methoxy-4-(1-methylethoxy)-2-[[[2-[4-(1-ethylethoxy)phenyl]ethyl]thio]methyl]benzene 
• 380375-83-7 4-bromo-5-[[2-(4-hydroxyphenyl)ethylsulfonyl]methyl]-2-methoxyphenol 
• 365572-11-8 2-[2-bromo-4-methoxy-5-(1-methylethoxy)phenylmethyl]-2-[2-[4-(1-methylethoxy)-phenyl]ethyl]propanediacid dimethyl ester 
• 365572-13-0 2-(2-bromo-5-isopropoxy-4-methoxybenzyl)-4-(4-isopropoxyphenyl)butyramide 
• 365572-12-9 2-(2-bromo-5-isopropoxy-4-methoxybenzyl)-4-(4-isopropoxyphenyl)butyric acid 
• 365572-15-2 α-(2-bromo-5-hydroxy-4-methoxyphenylmethyl)-4-hydroxy-benzenebutaneamide 
• 365572-10-7 2-[2-[4-(1-methylethoxy)phenyl]ethyl]propanedioic acid dimethyl ester 

Relevant articles and documents

Discovery of tertiary amine and indole derivatives as potent RORγt inverse agonists

A novel series of tertiary amines as retinoid-related orphan receptor gamma-t (RORγt) inverse agonists was discovered through agonist/inverse agonist conversion. The level of RORγt inhibition can be enhanced by modulating the conformational disruption of H12 in RORγt LBD. Linker exploration and rational design led to the discovery of more potent indole-based RORγt inverse agonists.

Novel derivatives and analogues of galanthamin

New compounds of general formula I 1

12H-[2]-benzothiepino[6,5a,5-bc]benzofuran: Synthesis of a sulfur-analog of galanthamine

An analog of the anti-Alzheimer drug galanthamine, carrying a SO2-moiety instead of an amino-functionality, has been synthesized as a racemic mixture using tandem cyclization techniques to form a new four membered heterocyclic ring system.

9-(Arylalkyl or aroylalkyl)-1-oxa-4,9-diazaspiro(5.5)undecan-3-ones

Compounds useful in the prevention and/or treatment of hypertension, congestive heart failure, arrhythmia, migraine, vasospastic disorders, and asthma are represented by the formula STR1 wherein: R1 is STR2 wherein X is hydrogen, lower alkyl, lower alkoxy, halo, carboxamido or hydroxy; m is 1, 2 or 3; and n is 1, 2 or 3; R2, R3 and R4 are independently hydrogen or lower alkyl; and the pharmaceutically acceptable acid addition salts thereof.