3660-10-4

Usage

Appearance

White crystalline solid
The compound has a solid, crystalline structure and is white in color.

Molecular weight

194.65 g/mol
The mass of one mole of the compound is 194.65 grams.

Uses

Reagent in organic synthesis, production of pharmaceuticals and agrochemicals, preparation of polymers and other chemical compounds
The compound serves as a versatile reagent in various chemical processes, including the synthesis of pharmaceuticals, agrochemicals, polymers, and other compounds.

Reactivity

Chloromethyl group makes it reactive towards nucleophiles
The presence of the chloromethyl group in the molecule allows it to react with nucleophiles, making it a useful intermediate in the synthesis of various organic compounds.

Safety

Handle with care and in accordance with appropriate safety measures
Due to its chemical properties, it is crucial to handle 1,4,6-Trioxaspiro[4.4]nonane, 2-(chloromethyl)- carefully and follow proper safety protocols to minimize risks.

Upstream product

• 96-48-0 4-butanolide 
• 106-89-8 epichlorohydrin 

Downstream Products

• 96-48-0 4-butanolide 
• 121033-56-5 2-Benzylsulfanylmethyl-1,4,6-trioxa-spiro[4.4]nonane 
• 81214-94-0 2-Benzylaminomethyl-1,4,6-trioxa-spiro-<4,4>-nonan 
• 81214-95-1 1-[Benzyl-(1,4,6-trioxa-spiro[4.4]non-2-ylmethyl)-amino]-3-{4-[1-(4-{3-[benzyl-(1,4,6-trioxa-spiro[4.4]non-2-ylmethyl)-amino]-2-hydroxy-propoxy}-phenyl)-1-methyl-ethyl]-phenoxy}-propan-2-ol 

Relevant academic research and scientific papers

PERFLUORINATED RESINSULFONIC ACID - A CATALYST FOR CERTAIN ORGANIC REACTIONS.

The purpose of this work was to examine the possibility of using, as a catalyst in certain organic reactions, the perfluorinated resinsulfonic acid F-4SK in the H form, which is an analog of the perfluorinated resinsulfonic acid Nafion-H. To compare catalyst activity of the perfluorinated resinsulfonic acid in decomposition of cumene hydroperoxide, CHP was also decomposed in presence of KU-2 resin. It was found that during repeated use over a period of 150 h the activity of KU-2 catalyst under analogous conditions fell by 4-6%. During the same time the activity of the perfluorinated resinsulfonic acid remained unchanged. It is also known that the presence of a strong acid in the reaction mixture causes formation of by-products, namely the products of condensation of phenol with acetone and dimethylphenylcarbinol, and of dehydration of dimethylphenylcarbinol, with formation of alpha -methylstyrene and products of greater complexity.

SOME REACTIONS OF 2-SUBSTITUTED SPIRO ORTHO ESTERS UNDER INTERPHASE CATALYSIS CONDITIONS

The nucleophilic substitution of halogen in 2-halogeno spiro ortho esters was realized by the salts of carboxylic acids in the presence of the interphase transfer catalysts triethylbenzylammonium chloride and 18-crown-6 polyether.The 2-acetoxy spiro ortho esters are hydrolyzed to the corresponding alcohols in the presence of the same catalyst.The hydroxyl-containing spiro ortho esters are converted into normal esters by the action of acid anhydrides or chlorides.